COL3 antibody (AA 1301-1400) (Biotin)

Catalog No. ABIN669983

Product Details anti-COL3 Antibody (Biotin)

Target: COL3 (Collagen, Type III (COL3))

Binding Specificity: AA 1301-1400

Reactivity: Human, Rat, Mouse, Dog, Rabbit

Host: Rabbit

Clonality: Polyclonal

Conjugate: This COL3 antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Specificity: This antibody is produced with an immunogen contained within the COLFI propeptide region, it will only recognize the full length Collagen III protein and not the mature form.

Cross-Reactivity: Dog, Human, Mouse, Rabbit, Rat

Predicted Reactivity: Cow,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human Collagen alpha 1(III) chain (C-terminal propeptide)

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for COL3

Target: COL3 (Collagen, Type III (COL3))

Alternative Name: Collagen 3 (COL3 Products)

Synonyms: PT antibody, RPRGL2 antibody, THPH1 antibody, Cf-2 antibody, Cf2 antibody, FII antibody, thrombin antibody, prothrombin antibody, coagulation factor II, thrombin antibody, coagulation factor II antibody, F2 antibody

Background:

Synonyms: EDS4A, Collagen alpha-1(III) chain, COL3A1

Background: Collagen type III occurs in most soft connective tissues along with type I collagen. Involved in regulation of cortical development. Is the major ligand of GPR56 in the developing brain and binding to GPR56 inhibits neuronal migration and activates the RhoA pathway by coupling GPR56 to GNA13 and possibly GNA12.

Gene ID: 1281

UniProt: P02461