LARS antibody

Catalog No. ABIN6719336

Product Details anti-LARS Antibody

Target: LARS (Leucyl-tRNA Synthetase (LARS))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This LARS antibody is un-conjugated

Application: Western Blotting (WB), ELISA

Purpose: Rabbit IgG polyclonal antibody for Leucyl tRNA synthetase/LARS detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for Leucyl tRNA synthetase/LARS detection. Tested with WB, Direct ELISA in Human,Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogen: E. coli-derived human Leucyl tRNA synthetase/LARS recombinant protein (Q628-Q855).

Isotype: IgG

Application Details

Application Notes:

Application details: Western blot|0.1-0.5 μg/mL Direct ELISA|0.1-0.5 μg/mL

Comment:

Tested Species: In-house tested species with positive results. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for LARS

Target: LARS (Leucyl-tRNA Synthetase (LARS))

Alternative Name: LARS (LARS Products)

Synonyms: HSPC192 antibody, LARS1 antibody, LEURS antibody, LEUS antibody, LRS antibody, PIG44 antibody, RNTLS antibody, hr025Cl antibody, CG7479 antibody, Dmel\\CG7479 antibody, LeuRS antibody, F21M12.1 antibody, F21M12_1 antibody, BA4991 antibody, DDBDRAFT_0183834 antibody, DDBDRAFT_0231251 antibody, DDB_0183834 antibody, DDB_0231251 antibody, 2310045K21Rik antibody, 3110009L02Rik antibody, AW536573 antibody, mKIAA1352 antibody, leucyl-tRNA synthetase antibody, Leucyl-tRNA synthetase, mitochondrial antibody, ATP binding/leucine-tRNA ligases/aminoacyl-tRNA ligase antibody, leucine--tRNA ligase antibody, leucyl-tRNA synthetase LeuS antibody, leucyl-tRNA ligase antibody, leucine-tRNA ligase antibody, LARS antibody, LeuRS-m antibody, AT1G09620 antibody, leuS antibody, APH_RS02290 antibody, mleuS antibody, Lars antibody

Background:

Synonyms: Leucine--tRNA ligase, cytoplasmic, Leucyl-tRNA synthetase, LeuRS, LARS, KIAA1352

Background: Leucyl-tRNA synthetase, cytoplasmic is an enzyme that in humans is encoded by the LARS gene. This gene is mapped to 5q32. It encodes a cytosolic leucine-tRNA synthetase, a member of the class I aminoacyl-tRNA synthetase family. The encoded enzyme catalyzes the ATP-dependent ligation of L-leucine to tRNA(Leu). It is found in the cytoplasm as part of a multisynthetase complex and interacts with the arginine tRNA synthetase through its C-terminal domain. A mutation in this gene was found in affected individuals with infantile liver failure syndrome 1. Alternatively spliced transcript variants of this gene have been observed.

Gene ID: 51520

UniProt: Q9P2J5

Pathways: EGFR Signaling Pathway