ARPC1B antibody (AA 293-372)

Catalog No. ABIN6719390

Product Details anti-ARPC1B Antibody

Target: ARPC1B (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B))

Binding Specificity: AA 293-372

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This ARPC1B antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Purpose: Rabbit IgG polyclonal antibody for ARP2/3 subunit 1B/ARPC1B detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Cross-Reactivity (Details): No cross reactivity with other proteins.

Characteristics: Rabbit IgG polyclonal antibody for ARP2/3 subunit 1B/ARPC1B detection. Tested with WB, IHC-P, Direct ELISA in Human,Mouse,Rat.

Purification: Immunogen affinity purified.

Immunogen: E.coli-derived human ARP2/3 subunit 1B/ARPC1B recombinant protein (Position: Q293-K372).

Isotype: IgG

Application Details

Application Notes:

Application details: Western blot|0.1-0.5 μg/mL Immunohistochemistry(Paraffin-embedded Section)|0.5-1 μg/mL Direct ELISA|0.1-0.5 μg/mL

Comment:

Tested Species: In-house tested species with positive results. By Heat: Boiling the paraffin sections in 10mM citrate buffer, pH6.0, for 20mins is required for the staining of formalin/paraffin sections. Other applications have not been tested. Optimal dilutions should be determined by end users.

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Add 0.2 mL of distilled water will yield a concentration of 500 μg/mL.

Buffer: Each vial contains 4 mg Trehalose, 0.9 mg NaCl, 0.2 mg Na2HPO4, 0.05 mg Sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: At -20°C for one year. After reconstitution, at 4°C for one month.
It can also be aliquotted and stored frozen at -20 °C for a longer time. Avoid repeated freezing and thawing.

Target Details for ARPC1B

Target: ARPC1B (Actin Related Protein 2/3 Complex, Subunit 1B, 41kDa (ARPC1B))

Alternative Name: ARPC1B (ARPC1B Products)

Synonyms: ARC41 antibody, p40-ARC antibody, p41-ARC antibody, cb871 antibody, arpc1a antibody, fj15h02 antibody, zgc:64056 antibody, wu:fj08e12 antibody, wu:fj15h02 antibody, 41kDa antibody, AA408064 antibody, AA408534 antibody, AA571392 antibody, AF007010 antibody, AW208418 antibody, L72 antibody, SOP2Hs antibody, ACTIN-RELATED PROTEIN C1 antibody, ARPC1 antibody, F16D14.14 antibody, F16D14_14 antibody, actin-related protein C1B antibody, arc41 antibody, p40-arc antibody, p41-arc antibody, actin related protein 2/3 complex subunit 1B antibody, actin related protein 2/3 complex, subunit 1B antibody, ARP2/3 complex 41 kDa subunit antibody, actin-related protein C1B antibody, actin-related protein 2/3 complex subunit 1B antibody, actin related protein 2/3 complex subunit 1B S homeolog antibody, ARPC1B antibody, Arpc1b antibody, EHI_094120 antibody, arpc1b antibody, LOC100410640 antibody, arpc1b.S antibody

Background:

Synonyms: Actin-related protein 2/3 complex subunit 1B, Arp2/3 complex 41 kDa subunit, p41-ARC, ARPC1B, ARC41

Background: Actin-related protein 2/3 complex subunit 1B is a protein that in humans is encoded by the ARPC1B gene. It is mapped to 7q22.1. This gene encodes one of seven subunits of the human Arp2/3 protein complex. This subunit is a member of the SOP2 family of proteins and is most similar to the protein encoded by gene ARPC1A. The similarity between these two proteins suggests that they both may function as p41 subunit of the human Arp2/3 complex that has been implicated in the control of actin polymerization in cells. It is possible that the p41 subunit is involved in assembling and maintaining the structure of the Arp2/3 complex. Multiple versions of the p41 subunit may adapt the functions of the complex to different cell types or developmental stages. This protein also has a role in centrosomal homeostasis by being an activator and substrate of the Aurora A kinase.

Gene ID: 10095

UniProt: O15143

Pathways: RTK Signaling, Regulation of Actin Filament Polymerization