CD45RA antibody (Alexa Fluor 488)

Catalog No. ABIN6722065

This Mouse Monoclonal antibody specifically detects CD45RA in FACS. It exhibits reactivity toward Human.

Quick Overview for CD45RA antibody (Alexa Fluor 488) (ABIN6722065)

Target: CD45RA

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD45RA antibody is conjugated to Alexa Fluor 488

Application: Flow Cytometry (FACS)

Clone: HI100

Product Details anti-CD45RA Antibody (Alexa Fluor 488)

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD45RA

Target: CD45RA

Alternative Name: CD45RA

Background:

Synonyms: Receptor-type tyrosine-protein phosphatase C,Ptprc,L-CA,Ly-5,T200,CD45

Background: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naive T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

Gene ID: 5788

UniProt: P08575