CD45RA antibody (Alexa Fluor 647)

Catalog No. ABIN6722066

The Mouse Monoclonal anti-CD45RA antibody has been validated for FACS. It is suitable to detect CD45RA in samples from Human.

Quick Overview for CD45RA antibody (Alexa Fluor 647) (ABIN6722066)

Target: CD45RA

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This CD45RA antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS)

Clone: HI100

Product Details anti-CD45RA Antibody (Alexa Fluor 647)

Isotype: IgG2b kappa

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: PBS with 0.05 % Proclin300, 1 % BSA

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C

Storage Comment: Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.

Target Details for CD45RA

Target: CD45RA

Alternative Name: CD45RA

Background:

Synonyms: Receptor-type tyrosine-protein phosphatase C,Ptprc,L-CA,Ly-5,T200,CD45

Background: CD45RA is a 205-220 kD single chain type I glycoprotein. It is an exon 4 splice variant of the tyrosine phosphatase CD45. The CD45RA isoform is expressed on resting/naive T cells, medullary thymocytes, B cells and monocytes. CD45RA enhances both T cell receptor and B cell receptor signaling. CD45 non-covalently associates with lymphocyte phosphatase-associated phosphoprotein (LPAP) on T and B lymphocytes. CD45 has been reported to be associated with several other cell surface antigens including CD1, CD2, CD3, and CD4. CD45 has also been reported to bind galectin-1. CD45 isoform expression can change in response to cytokines.

Gene ID: 5788

UniProt: P08575