Integrin Alpha2b antibody (APC)
Quick Overview for Integrin Alpha2b antibody (APC) (ABIN6728307)
Target
See all Integrin Alpha2b (CD41) AntibodiesReactivity
Host
Clonality
Conjugate
Application
Clone
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Isotype
- IgG1, kappa
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Application Notes
- Check your vial before the experiment. Since applications vary, the appropriate dilutions must be determined for individual use. We suggest each investigator should titrate the reagent to obtain optimal results [The recommended concentration is 0.1-1 μg/10^6 cells in 100 μL volume].
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Comment
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Matching Isotype Control: APC Rat IgG1, κ Isotype Control (ABIN7469823)
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Restrictions
- For Research Use only
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Concentration
- 0.2 mg/mL
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Buffer
- PBS with 0.05 % Proclin300, 1 % BSA
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C
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Storage Comment
- Store at 2~8°C and protected from prolonged exposure to light. Do not freeze.
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- Integrin Alpha2b (CD41)
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Alternative Name
- CD41
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Background
- Itga2b,GPalpha Iib,CD41,GPIIb,CD41, also known as integrin α2b and GPIIb, is a transmembrane glycoprotein that is expressed by platelets and megakaryocytes. It was reported that CD41 is also expressed on hematopoietic progenitors. CD41 associates with CD61 (integrin β3) to form complexes that interact with fibrinogen, fibronectin, von Willebrand factor, and thrombin. CD41 is required for platelet adhesion and aggregation. Defect of CD41 leads to disorders of coagulation.
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Gene ID
- 16399
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UniProt
- Q9QUM0
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Pathways
- Integrin Complex
Target
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