GSK3 alpha antibody (pTyr216, pTyr279)

Catalog No. ABIN6735075

The Rabbit Polyclonal anti-GSK3 alpha antibody is suitable to detect GSK3 alpha in samples from Human. It has been validated for WB.

Quick Overview for GSK3 alpha antibody (pTyr216, pTyr279) (ABIN6735075)

Target: GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GSK3 alpha antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-GSK3 alpha Antibody

Binding Specificity: pTyr216, pTyr279

Specificity: Recognizes human GSK3a phosphorylated at Tyr279 and GSK3b phosphorylated at Tyr216. Reactivity: Human, mouse, and rat GSK-3 /.

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Purification: Immunoaffinity Chromatography

Immunogen: Synthetic phosphopeptide derived from a region of human GSK-3 / that contains tyrosine 279/216. The sequence is conserved in ratGSK-3 and mouse, rat, and frog GSK-3.

Application Details

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS (without Mg2+, Ca2+), 1 mg/mL BSA (IgG, protease free), pH 7.2, 0.1% sodium azide, 50% glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Long term: -20°C, Short term: +4°C, Avoid freeze-thaw cycles.

Target Details for GSK3 alpha

Target: GSK3 alpha (GSK3a) (Glycogen Synthase Kinase 3 alpha (GSK3a))

Alternative Name: GSK3A / GSK3 Alpha

Background: Standard Gene Symbol: GSK3A, Gene Family: Protein Kinase, Gene Subfamily: GSK-3, Synonyms: GSK3A, GSK-3 alpha, GSK3 alpha

Gene ID: 2931

UniProt: P49840

Pathways: PI3K-Akt Signaling, WNT Signaling, Fc-epsilon Receptor Signaling Pathway, EGFR Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Cellular Glucan Metabolic Process, Regulation of Muscle Cell Differentiation, Regulation of G-Protein Coupled Receptor Protein Signaling, ER-Nucleus Signaling, Regulation of Carbohydrate Metabolic Process, BCR Signaling, Warburg Effect