RAF1 antibody (pTyr340, pTyr341)

Catalog No. ABIN6735131

This Rabbit Polyclonal antibody specifically detects RAF1 in WB and ICC. It exhibits reactivity toward Human.

Quick Overview for RAF1 antibody (pTyr340, pTyr341) (ABIN6735131)

Target: RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAF1 antibody is un-conjugated

Application: Western Blotting (WB), Immunocytochemistry (ICC)

Product Details anti-RAF1 Antibody

Binding Specificity: pTyr340, pTyr341

Specificity: Reactivity: Human c-Raf. Mouse and rat c-Raf (100% homologous) have not been tested, but are expected to react.

Cross-Reactivity: Mouse (Murine), Rat (Rattus)

Purification: Immunoaffinity Chromatography

Immunogen: Produced against a chemically synthesized phosphopeptide derived from a region of human c-Raf that contains tyrosines 340 and 341. The sequence is conserved in mouse and rat.

Application Details

Application Notes: ICC, WB

Restrictions: For Research Use only

Handling

Format: Liquid

Buffer: PBS (without Mg2+, Ca2+), 1 mg/mL BSA (IgG, protease free), pH 7.2, 0.1% sodium azide, 50% glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C/-20 °C

Storage Comment: Long term: -20°C, Short term: +4°C, Avoid freeze-thaw cycles.

Target Details for RAF1

Target: RAF1 (V-Raf-1 Murine Leukemia Viral Oncogene Homolog 1 (RAF1))

Alternative Name: RAF1 / RAF

Background: Standard Gene Symbol: RAF1, Gene Family: Protein Kinase, Gene Subfamily: Raf, Synonyms: RAF1, C-Raf, C-raf-1, CRAF, NS5, Raf-1, Proto-oncogene c-RAF, Oncogene RAF1, RAF, Raf1 kinase

Gene ID: 5894

UniProt: P04049

Pathways: MAPK Signaling, RTK Signaling, Fc-epsilon Receptor Signaling Pathway, Neurotrophin Signaling Pathway, cAMP Metabolic Process, Stem Cell Maintenance, Hepatitis C, Autophagy, Signaling of Hepatocyte Growth Factor Receptor, VEGF Signaling, BCR Signaling