GRIN2B antibody (N-Term)

Catalog No. ABIN6735390

This Rabbit Polyclonal antibody specifically detects GRIN2B in WB and IHC (fro). It exhibits reactivity toward Rat.

Quick Overview for GRIN2B antibody (N-Term) (ABIN6735390)

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GRIN2B antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Frozen Sections) (IHC (fro))

Product Details anti-GRIN2B Antibody

Binding Specificity: N-Term

Specificity: Specific for the NMDA receptor-2B isoform and exhibits no cross-reactivity with other receptor subtypes. Reacts with the NMDA receptor-2B from rat. Reactivity has been confirmed in Western blots using lysates from rat brain and by immunocytochemical staining of rat brain tissue. Reactivity with other species has not been tested. However, the amino acid sequences of rat, human and mouse NMDAR2B proteins are highly similar over the region of protein used to prepare this antibody.

Purification: Immunoaffinity Chromatography

Immunogen: Fusion protein including a 251 amino acid sequence from the N-terminal portion of the rat NMDAR 2B protein.

Isotype: IgG

Application Details

Application Notes: IHC-Fr, WB (1 µg/mL)

Restrictions: For Research Use only

Handling

Buffer: PBS, pH 7.2, 0.1% sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C/-20 °C

Storage Comment: Long term: Add glycerol (40-50%) -20°C, Short term: +4°C

Target Details for GRIN2B

Target: GRIN2B (Glutamate Receptor, Ionotropic, N-Methyl D-Aspartate 2B (GRIN2B))

Alternative Name: GRIN2B / NMDAR2B / NR2B

Background: Standard Gene Symbol: GRIN2B, Gene Family: Ion Channel, Gene Subfamily: Glutamate receptor - ionotropic (NMDA receptor), Synonyms: GRIN2B, GluN2B, GluR epsilon 2, NMDA receptor 2B, NMDAR2B, NR2B, NR3, MRD6, HNR3

Gene ID: 2904

UniProt: Q13224

Pathways: Response to Growth Hormone Stimulus, Synaptic Membrane, Feeding Behaviour, Regulation of long-term Neuronal Synaptic Plasticity