RIPK1 antibody (AA 411-460)

Catalog No. ABIN6735883

This anti-RIPK1 antibody is a Rabbit Polyclonal antibody detecting RIPK1 in WB. Suitable for Human, Cow, Horse and Monkey.

Quick Overview for RIPK1 antibody (AA 411-460) (ABIN6735883)

Target: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Reactivity: Human, Cow, Horse, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RIPK1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-RIPK1 Antibody

Binding Specificity: AA 411-460

Specificity: Human RIPK1

Predicted Reactivity: Percent identity by BLAST analysis: Human, Bovine (100%) Dog (91%) Horse (83%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa411-460 of human RIPK1 (Q13546, NP_003795). Percent identity by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Bovine (100%), Elephant, Dog (91%), Galago, Horse (83%).

Type of Immunogen: Synthetic peptide

Isotype: IgG

Application Details

Application Notes: Approved: WB (0.2 - 1 μg/mL)

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: After adding water, will consist of PBS buffer with 2 % sucrose

Concentration: Lot specific

Buffer: Lyophilized.

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for RIPK1

Target: RIPK1 (Receptor (TNFRSF)-Interacting serine-threonine Kinase 1 (RIPK1))

Alternative Name: RIPK1 / RIP

Background: Name/Gene ID: RIPK1
Subfamily: RIP
Family: Protein Kinase

Synonyms: RIPK1, Cell death protein RIP, Receptor interacting protein, RIP1, RIP, RIP-1, Protein kinase rip, Receptor-interacting protein 1, Rinp

Gene ID: 8737

NCBI Accession: NP_003795

UniProt: Q13546

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Inositol Metabolic Process, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Toll-Like Receptors Cascades, Negative Regulation of intrinsic apoptotic Signaling, SARS-CoV-2 Protein Interactome, Ubiquitin Proteasome Pathway