BAK1 antibody (AA 21-120) (Cy5)

Catalog No. ABIN674413

Product Details anti-BAK1 Antibody (Cy5)

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Binding Specificity: AA 21-120

Reactivity: Human, Mouse, Rat, Chicken

Host: Rabbit

Clonality: Polyclonal

Conjugate: This BAK1 antibody is conjugated to Cy5

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Chicken, Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from mouse BAK

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for BAK1

Target: BAK1 (BCL2-Antagonist/killer 1 (BAK1))

Alternative Name: BAK (BAK1 Products)

Synonyms: BAK antibody, BAK-LIKE antibody, BCL2L7 antibody, CDN1 antibody, Bak antibody, N-BAK1 antibody, N-Bak antibody, Bak1 antibody, bak antibody, bak1 antibody, BCL2 antagonist/killer 1 antibody, BCL2-antagonist/killer 1 antibody, BCL2 antagonist/killer 1 L homeolog antibody, BAK1 antibody, Bak1 antibody, bak1.L antibody

Background:

Synonyms: Apoptosis Regulator Bak, BAK 1, BAK, BAK like, Bak NT, BAK1, Bcl 2 homologous antagonist/killer, Bcl 2 like 7 protein, Bcl2 homologous antagonist killer, Bcl2 like 7 Protein, BCL2-antagonist/killer 1, BCL2L7, CDN 1, CDN1, Cell death inhibitor 1, MGC117255, MGC3887, NBak, Pro apoptotic protein BAK, BAX_MOUSE.

Background: In the presence of an appropriate stimulus, accelerates programmed cell death by binding to, and antagonizing the anti-apoptotic action of BCL2.

Gene ID: 12018

UniProt: O08734

Pathways: Apoptosis, Steroid Hormone Mediated Signaling Pathway, ER-Nucleus Signaling, Positive Regulation of Endopeptidase Activity, Unfolded Protein Response