SHP1 antibody (AA 245-294)

Catalog No. ABIN6747490

The Rabbit Polyclonal anti-SHP1 antibody is suitable to detect SHP1 in samples from Human and Monkey. It has been validated for WB.

Quick Overview for SHP1 antibody (AA 245-294) (ABIN6747490)

Target: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Reactivity: Human, Monkey

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SHP1 antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-SHP1 Antibody

Binding Specificity: AA 245-294

Specificity: Human PTPN6

Predicted Reactivity: Percent identity by BLAST analysis: Human (100%) Mouse, Rat, Dog, Bovine, Rabbit, Horse, Pig, Guinea pig, Chicken, Xenopus (92%) Zebrafish (85%).

Purification: Immunoaffinity purified

Immunogen: Synthetic peptide located between aa245-294 of human PTPN6 (P29350, NP_002822). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Gibbon, Monkey, Galago, Marmoset, Platypus (100%), Mouse, Rat, Elephant, Dog, Bovine, Bat, Rabbit, Horse, Pig, Opossum, Guinea pig, Turkey, Zebra finch, Chicken, Xenopus, Stickleback, Zebrafish (92%), Salmon (85%).

Type of Immunogen: Synthetic peptide

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Lyophilized

Reconstitution: Distilled water

Concentration: Lot specific

Buffer: Lyophilized from PBS with 2 % sucrose

Handling Advice: Avoid repeat freeze-thaw cycles.

Storage: 4 °C,-20 °C

Storage Comment: Long term: -20°C, the use of 50% glycerol is recommended if storing aliquots in -20°C for long term use (up to 1 year)
Short term (less than 1 week): 4°C. Avoid freeze-thaw cycles.

Target Details for SHP1

Target: SHP1 (PTPN6) (Protein-tyrosine Phosphatase 1C (PTPN6))

Alternative Name: PTPN6 / SHP-1

Background: Name/Gene ID: PTPN6
Subfamily: NT2
Family: Protein Phosphatase

Synonyms: PTPN6, HCP, HPTP1C, Hematopoietic cell phosphatase, PTP-1C, SH-PTP1, SHP-1L, SHP-1, Shptp1, HCPH, PTP1C, SHP1

Gene ID: 5777

NCBI Accession: NP_002822

UniProt: P29350

Pathways: JAK-STAT Signaling, TCR Signaling, TLR Signaling, Nuclear Receptor Transcription Pathway, Positive Regulation of Peptide Hormone Secretion, Steroid Hormone Mediated Signaling Pathway, Response to Growth Hormone Stimulus, Regulation of Leukocyte Mediated Immunity, CXCR4-mediated Signaling Events, Signaling Events mediated by VEGFR1 and VEGFR2, BCR Signaling