EIF4G2 antibody (AA 41-150) (HRP)

Catalog No. ABIN675348

Product Details anti-EIF4G2 Antibody (HRP)

Target: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Binding Specificity: AA 41-150

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This EIF4G2 antibody is conjugated to HRP

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Sheep,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human DAP-5

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Handling Advice: Do NOT add Sodium Azide! Use of Sodium Azide will inhibit enzyme activity of horseradish peroxidase.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for EIF4G2

Target: EIF4G2 (Eukaryotic Translation Initiation Factor 4 gamma 2 (EIF4G2))

Alternative Name: DAP-5/p97 (EIF4G2 Products)

Synonyms: AAG1 antibody, DAP5 antibody, NAT1 antibody, P97 antibody, NAT1B antibody, eif4g2 antibody, hm:zeh1307 antibody, wu:fa14h01 antibody, wu:fb44h01 antibody, wu:fb59c06 antibody, wu:fc21b05 antibody, EIF4G2 antibody, AA589388 antibody, DAP-5 antibody, E130105L11Rik antibody, Nat1 antibody, Natm1 antibody, p97 antibody, NAT1A antibody, im:7148615 antibody, wu:fb81f07 antibody, wu:fb82b06 antibody, wu:fb98h08 antibody, dap5 antibody, eif4g2.L antibody, nat1 antibody, eukaryotic translation initiation factor 4 gamma 2 antibody, eukaryotic translation initiation factor 4, gamma 2b antibody, eukaryotic translation initiation factor 4, gamma 2 antibody, eukaryotic translation initiation factor 4 gamma, 2 antibody, eIF4G-related protein NAT1 antibody, eukaryotic translation initiation factor 4, gamma 2a antibody, eukaryotic translation initiation factor 4 gamma, 2 S homeolog antibody, EIF4G2 antibody, eif4g2b antibody, Eif4g2 antibody, nat1 antibody, eif4g2a antibody, eif4g2.S antibody

Background:

Synonyms: Death Associated Protein-5, Death associated protein 5, Eukaryotic translation initiation factor 4 gamma 2, Nat1, Novel APOBEC-1 target 1, Translation repressor NAT1.

Background: Death Associated Protein 5 (DAP5) is a 97 kDa protein with high amino acid sequence homology to Eukaryotic Translation Initiation Factor 4G (eIF4G). Compared with eIF4G, DAP5 lacks the N-terminal region necessary for cap-dependent translation and has a unique C-terminal part functioning as a regulator for interferon-gamma induced cell death. During apoptosis, DAP5 is cleaved at Asp790. The C-terminal truncated form of DAP5 functions as a cap-independent translation initiation factor responsible for the mediation of its own translation during apoptosis.

Gene ID: 1982