Caspase 8 antibody (AA 217-384) (FITC)

Catalog No. ABIN2618009

This Rabbit Polyclonal antibody specifically detects Caspase 8 in WB. It exhibits reactivity toward Human.

Quick Overview for Caspase 8 antibody (AA 217-384) (FITC) (ABIN2618009)

Target: Caspase 8 (CASP8)

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This Caspase 8 antibody is conjugated to FITC

Application: Western Blotting (WB)

Product Details anti-Caspase 8 Antibody (FITC)

Binding Specificity: AA 217-384

Specificity: Human CASP8 / Caspase 8

Purification: Affinity purified

Immunogen: Recombinant CASP8 (Ser217-Asp384) expressed in E. coli.

Type of Immunogen: Recombinant protein

Isotype: IgG

Application Details

Application Notes: Approved: WB (1:100 - 1:400)

Usage: The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

Comment:

Target Species of Antibody: Human

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: Lot specific

Buffer: PBS,  pH 7.4, 0.02 % sodium azide, 50 % glycerol.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C,-80 °C

Storage Comment: Store frozen product at or below -20°C. Thawed product may be stored for 2-4 weeks at 4°C. For optimal storage, aliquot to smaller portions and store at -20°C to -70°C. Avoid freeze-thaw cycles.

Target Details for Caspase 8

Target: Caspase 8 (CASP8)

Alternative Name: CASP8 / Caspase 8

Background: Name/Gene ID: CASP8
Subfamily: Cysteine C14
Family: Protease

Synonyms: CASP8, ALPS2B, Apoptotic protease Mch-5, Apoptotic cysteine protease, Casp-8, Caspase-8, CAP4, Caspase 8, MACH, MCH5, MORT1-associated ced-3 homolog, ICE-like apoptotic protease 5, Pro Caspase 8, FADD-like ICE, FLICE, MACH-alpha-1/2/3 protein, MACH-beta-1/2/3/4 protein

Gene ID: 841

Pathways: Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Activation of Innate immune Response, Tube Formation, Positive Regulation of Endopeptidase Activity, Toll-Like Receptors Cascades