GRB10 antibody (pTyr67)
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- Target See all GRB10 Antibodies
- GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))
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Binding Specificity
- pTyr67
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This GRB10 antibody is un-conjugated
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Application
- ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Human, Mouse
- Predicted Reactivity
- Horse,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic phosphopeptide derived from human GRB10 around the phosphorylation site of Tyr67 [SL(p-Y)SA]
- Isotype
- IgG
- Top Product
- Discover our top product GRB10 Primary Antibody
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- Application Notes
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ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- 4 °C,-20 °C
- Storage Comment
- Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
- Expiry Date
- 12 months
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- Target
- GRB10 (Growth Factor Receptor-Bound Protein 10 (GRB10))
- Alternative Name
- GRB10 (GRB10 Products)
- Synonyms
- grb10 antibody, zgc:91987 antibody, GRB10 antibody, grb-10 antibody, grb-ir antibody, irbp antibody, meg1 antibody, rss antibody, LOC100224775 antibody, 5730571D09Rik antibody, AI325020 antibody, Meg1 antibody, mKIAA0207 antibody, RGD1566234 antibody, GRB-IR antibody, Grb-10 antibody, IRBP antibody, MEG1 antibody, RSS antibody, growth factor receptor bound protein 10 antibody, growth factor receptor-bound protein 10a antibody, growth factor receptor bound protein 10 L homeolog antibody, growth factor receptor-bound protein 10 antibody, GRB10 antibody, grb10a antibody, grb10 antibody, grb10.L antibody, LOC100434903 antibody, Grb10 antibody
- Background
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Synonyms: GRB IR, grb-10, GRB10 adaptor protein, GRBIR, Growth factor receptor bound protein 10, Insulin receptor binding protein, Insulin receptor binding protein GRB IR, IRBP, MEG1, RSS.
Background: GRB 10 belongs to a small family of adapter proteins that interact with receptor tyrosine kinases and signaling molecules. In particular, GRB 10 interacts with insulin receptors and insulin-like growth-factor receptors. Alternatively spliced transcript variants encoding different isoforms have been identified: overexpression of some of them inhibits tyrosine kinase activity and results in growth suppression. This gene is imprinted in a highly isoform- and tissue-specific manner.
- Gene ID
- 2887
- Pathways
- Regulation of Carbohydrate Metabolic Process, Signaling Events mediated by VEGFR1 and VEGFR2
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