PSMD9 antibody (AA 65-150)

Catalog No. ABIN685612

Product Details anti-PSMD9 Antibody

Target: PSMD9 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 9 (PSMD9))

Binding Specificity: AA 65-150

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This PSMD9 antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Dog,Cow,Pig,Horse,Chicken,Rabbit,Guinea Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human PSMD9

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for PSMD9

Target: PSMD9 (Proteasome (Prosome, Macropain) 26S Subunit, Non-ATPase, 9 (PSMD9))

Alternative Name: PSMD9 (PSMD9 Products)

Synonyms: Rpn4 antibody, p27 antibody, Bridge antibody, Bridge-1 antibody, zgc:92643 antibody, wu:fb30g07 antibody, PSMD9 antibody, psmd9 antibody, DDBDRAFT_0202482 antibody, DDBDRAFT_0232989 antibody, DDB_0202482 antibody, DDB_0232989 antibody, 1500011J20Rik antibody, 2610202L11Rik antibody, P27 antibody, proteasome 26S subunit, non-ATPase 9 antibody, proteasome 26S subunit, non-ATPase 9 L homeolog antibody, 26S proteasome non-ATPase regulatory subunit 9 antibody, proteasome (prosome, macropain) 26S subunit, non-ATPase, 9 antibody, PSMD9 antibody, Psmd9 antibody, psmd9 antibody, psmd9.L antibody, psmD9 antibody

Background:

Synonyms: Bridge-1, MGC8644, 26S proteasome non ATPase regulatory subunit 9, 26S proteasome regulatory subunit p27, Homolog of rat Bridge 1, p27, Proteasome prosome macropain 26S subunit non ATPase 9, Proteasome 26S non ATPase regulatory subunit 9, Proteasome 26S subunit non ATPase 9, PSMD 9, Rpn4.

Background: The 26S proteasome is a multicatalytic proteinase complex with a highly ordered structure composed of 2 complexes, a 20S core and a 19S regulator. The 20S core is composed of 4 rings of 28 non-identical subunits, 2 rings are composed of 7 alpha subunits and 2 rings are composed of 7 beta subunits. The 19S regulator is composed of a base, which contains 6 ATPase subunits and 2 non-ATPase subunits, and a lid, which contains up to 10 non-ATPase subunits. Proteasomes are distributed throughout eukaryotic cells at a high concentration and cleave peptides in an ATP/ubiquitin-dependent process in a non-lysosomal pathway. An essential function of a modified proteasome, the immunoproteasome, is the processing of class I MHC peptides. PSMD9 is a non-ATPase subunit of the 19S regulator.

Pathways: Positive Regulation of Peptide Hormone Secretion, Negative Regulation of Hormone Secretion, Mitotic G1-G1/S Phases, DNA Replication, Synthesis of DNA, Ubiquitin Proteasome Pathway