RAP1A antibody (AA 101-184)

Catalog No. ABIN687472

Product Details anti-RAP1A Antibody

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Binding Specificity: AA 101-184

Reactivity: Human, Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RAP1A antibody is un-conjugated

Application: Western Blotting (WB), ELISA, Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse

Predicted Reactivity: Rat,Cow,Horse,Chicken

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RAP1A

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
ELISA 1:500-1000
IHC-P 1:200-400
IHC-F 1:100-500
IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: 0.01M TBS( pH 7.4) with 1 % BSA, 0.02 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Shipped at 4°C. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.

Expiry Date: 12 months

Target Details for RAP1A

Target: RAP1A (RAP1A, Member of RAS Oncogene Family (RAP1A))

Alternative Name: RAP1A (RAP1A Products)

Synonyms: KREV-1 antibody, KREV1 antibody, RAP1 antibody, SMGP21 antibody, AI848598 antibody, G-22K antibody, Krev-1 antibody, Rap1 antibody, RAP-1A antibody, rap 1A antibody, wu:fc66g06 antibody, zgc:86676 antibody, krev-1 antibody, krev1 antibody, rap1 antibody, RAP1A, member of RAS oncogene family antibody, RAS-related protein 1a antibody, RAP1A, member of RAS oncogene family a antibody, RAP1A, member of RAS oncogene family L homeolog antibody, RAP1A antibody, Rap1a antibody, rap1aa antibody, rap1a.L antibody

Background:

Synonyms: RAP1, C21KG, G-22K, KREV1, KREV-1, SMGP21, Ras-related protein Rap-1A, GTP-binding protein smg p21A, Ras-related protein Krev-1, RAP1A

Background: Induces morphological reversion of a cell line transformed by a Ras oncogene. Counteracts the mitogenic function of Ras, at least partly because it can interact with Ras GAPs and RAF in a competitive manner. Together with ITGB1BP1, regulates KRIT1 localization to microtubules and membranes. Plays a role in nerve growth factor (NGF)-induced neurite outgrowth. Plays a role in the regulation of embryonic blood vessel formation. Involved in the establishment of basal endothelial barrier function. May be involved in the regulation of the vascular endothelial growth factor receptor KDR expression at endothelial cell-cell junctions.

Gene ID: 5906

UniProt: P62834

Pathways: TCR Signaling, Neurotrophin Signaling Pathway, Signaling of Hepatocyte Growth Factor Receptor