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CLTA/CLTB antibody (N-Term)

CLTA/CLTB Reactivity: Human IHC (f) Host: Mouse Monoclonal CLC-1421 unconjugated
Catalog No. ABIN6937001
  • Target See all CLTA/CLTB Antibodies
    CLTA/CLTB (Clathrin, Light Chain A/B (CLTA/CLTB))
    Binding Specificity
    • 3
    • 1
    • 1
    N-Term
    Reactivity
    • 5
    • 1
    • 1
    • 1
    • 1
    Human
    Host
    • 3
    • 1
    • 1
    Mouse
    Clonality
    • 3
    • 2
    Monoclonal
    Conjugate
    • 5
    This CLTA/CLTB antibody is un-conjugated
    Application
    • 4
    • 3
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    Immunohistochemistry (Formalin-fixed Sections) (IHC (f))
    Specificity
    Recognizes proteins of 31-44 kDa, which are identified as Clathrin Light Chains (both A B). Clathrin is composed of three heavy chains and three light chains, which associate non-covalently to form a triskelion structure. Clathrin light chain regulates the self-assembly of triskelions onto intracellular membranes. Clathrin light chain subunits (LCA and LCB) contribute to regulation of coated vesicle formation to sort proteins during receptor-mediated endocytosis and organelle biogenesis. LCA and LCB are encoded by two discrete genes. They share only 60 % homology, and have certain features in common. Both LCA and LCB undergo alternative mRNA splicing, which results in the generation of tissue-specific isoforms.
    Cross-Reactivity (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Purified recombinant N-terminal fragment of human Clathrin Light Chain
    Clone
    CLC-1421
    Isotype
    IgG2b kappa
    Top Product
    Discover our top product CLTA/CLTB Primary Antibody
  • Application Notes

    Known_Application: Immunohistochemistry (Formalin-fixed) (1-2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires heating tissue sections in 10 mM Tris with 1 mM EDTA, pH 9.0, for 45 min at 95°C followed by cooling at RT for 20 minutes), Optimal dilution for a specific application should be determined.

    Positive_Control: HeLa cells. Placenta or Prostate Carcinoma.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    CLTA/CLTB (Clathrin, Light Chain A/B (CLTA/CLTB))
    Alternative Name
    CLTA and CLTB (CLTA/CLTB Products)
    Synonyms
    lca antibody, zgc:73358 antibody, wu:fb61d08 antibody, wu:fj48d06 antibody, LCA antibody, clc antibody, DDBDRAFT_0169251 antibody, DDBDRAFT_0191305 antibody, DDB_0169251 antibody, DDB_0191305 antibody, clcb antibody, clathrin light chain A antibody, clathrin, light chain A antibody, Clathrin light chain antibody, clathrin light chain antibody, clathrin light chain B antibody, Clathrin light chain B antibody, CLTA antibody, clta antibody, clic-1 antibody, CLC1 antibody, clc antibody, CLTB antibody, clcb antibody, CNI00580 antibody, LOC5567495 antibody, CpipJ_CPIJ018056 antibody, PTRG_01988 antibody, PMAA_096950 antibody, SJAG_04517 antibody, TSTA_044110 antibody, PAS_chr1-4_0158 antibody
    Background
    Clathrin light chain A, Clathrin light chain B, Clathrin light chain LCA, Clathrin light chain LCB, Clathrin light polypeptide A, Clathrin light polypeptide B, Clathrin, light polypeptide (Lca), Clathrin, light polypeptide (Lcb), CLTA, CLTB,Clathrin, Light Chain
    Cellular localisation: Cytoplasmic
    Molecular Weight
    31-44kDa
    Gene ID
    1211, 1212, 484241
    UniProt
    P09496, P09497
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