IFNA1 antibody (Interferon, alpha 1)

Details for Product anti-IFNA1 Antibody No. ABIN6937475
Antigen
  • IFL
  • IFN
  • IFN-ALPHA
  • IFN-alphaD
  • IFNA13
  • IFNA@
  • Ifa1
  • IFN-ALPHA-1
  • IFN1@
  • IFNA1
  • IFN-alpha
  • IFN-gamma
  • IFNA
  • IFNA2
  • IFNA6
  • IFN-alpha1
  • interferon alpha 1
  • interferon, alpha 1
  • interferon, alpha 13
  • interferon
  • interferon-alpha 1
  • IFNA1
  • Ifna1
  • ifna1
  • IFNA13
  • IFNA3
Reactivity
Human
137
20
10
6
4
3
2
Host
Mouse
90
56
4
Clonality (Clone)
Monoclonal ()
Conjugate
This IFNA1 antibody is un-conjugated
8
5
5
4
4
3
3
3
3
3
3
3
2
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
1
Application
Flow Cytometry (FACS), Immunofluorescence (IF), Immunohistochemistry (Frozen Sections) (IHC (fro)), Western Blotting (WB)
85
58
30
28
13
7
7
6
6
3
3
2
2
2
1
Options
Immunogen Purified recombinant human IFN-alpha1
Clone Feb-48
Isotype IgG1, kappa
Purification Purified by Protein A/G
Plasmids, Primers & others Plasmids, Primers & others IFNA1 products on genomics-online (e.g. as negative or positive controls)
Antigen
Alternative Name IFNA1 (IFNA1 Antibody Abstract)
Background This MAb is specific for human interferon alpha 1 and does not cross react with human interferon alpha 2. Interferons are widely used therapeutic agents because of their anti-tumor and anti-viral effects and because of their modulatory effects on the immune system. These cytokines produce their effects by binding to the Type 1 Interferon- Receptor (IFNAR1). Down regulation of this receptor plays a key role in determining the magnitude and duration of cytokine signaling. This down regulation is influenced by phosphorylation of Serine 535 and 539 in the IFNAR1.
Molecular Weight 16-27kDa
Gene ID 3439
UniProt P01562
Pathways JAK-STAT Signaling, Hepatitis C
Application Notes

Positive Control: Stimulated human peripheral blood mononuclear cells.

Known Application: Flow Cytometry (0.5-1 μg/million cells), Western Blot (1-2 μg/mL), Immunohistochemistry (frozen), Immunofluorescence (0.5-1 μg/mL), Optimal dilution for a specific application should be determined.

Restrictions For Research Use only
Buffer 10 mM PBS without BSA and without Azide.
Preservative Azide free
Storage 4 °C,-80 °C
Storage Comment Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months.
Expiry Date 24 months
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