IL7R antibody (AA 21-236)
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- Target See all IL7R Antibodies
- IL7R (Interleukin 7 Receptor (IL7R))
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Binding Specificity
- AA 21-236
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This IL7R antibody is un-conjugated
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Application
- Western Blotting (WB), ELISA, Coating (Coat)
- Specificity
- The protein encoded by this gene is a receptor for interleukin 7 (IL7). The function of this receptor requires the interleukin 2 receptor, gamma chain (IL2RG), which is a common gamma chain shared by the receptors of various cytokines, including interleukins 2, 4, 7, 9, and 15. This protein has been shown to play a critical role in V(D)J recombination during lymphocyte development. Defects in this gene may be associated with severe combined immunodeficiency (SCID).
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant fragment (around aa 21-236) of human CD127 protein (IL7R) (exact sequence is proprietary)
- Clone
- IL7R-2751
- Isotype
- IgG2c kappa
- Top Product
- Discover our top product IL7R Primary Antibody
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- Application Notes
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Known_Application: ELISA (For coating, order Ab without BSA),Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: K562, HeLa, Daudi or Jurkat cells. Tonsil, Lymph Node or Spleen.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- IL7R (Interleukin 7 Receptor (IL7R))
- Alternative Name
- IL7R (IL7R Products)
- Synonyms
- IL7R antibody, CD127 antibody, IL-7Ralpha antibody, CDW127 antibody, IL-7R-alpha antibody, IL7RA antibody, ILRA antibody, IL-7RA antibody, interleukin 7 receptor antibody, IL7R antibody, Il7r antibody
- Background
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CD127, IL-7 receptor subunit alpha, IL-7R-alpha, IL7R, IL7RA, IL7R alpha, ILRA, Interleukin 7 receptor alpha chain, Interleukin 7 receptor,CD127 / IL7R (Marker of T-Reg Cells)
Cellular localisation: Cell Surface and Cytoplasmic - Molecular Weight
- 52-72kDa
- Gene ID
- 3575, 591742, 635723
- UniProt
- P16871
- Pathways
- JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Production of Molecular Mediator of Immune Response, Regulation of Cell Size
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