Integrin Alpha2b antibody
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- Target See all Integrin Alpha2b (CD41) Antibodies
- Integrin Alpha2b (CD41)
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This Integrin Alpha2b antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunofluorescence (IF)
- Specificity
- Reacts with a calcium-dependent complex of CD41/CD61, a dimer of 90 kDa and 140 kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/ 3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation.
- Cross-Reactivity (Details)
- Human.
- Purification
- 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
- Immunogen
- Recombinant full-length human Integrin alpha IIb protein
- Clone
- ITGA2B-1036
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CD41 Primary Antibody
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- Application Notes
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Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.
Positive_Control: KG1a, HEL cells and human platelets in lymph nodes or tonsils.
- Restrictions
- For Research Use only
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- Concentration
- 1.0 mg/mL
- Buffer
- Prepared in 10 mM PBS, WITHOUT BSA and Azide.
- Preservative
- Azide free
- Storage
- -20 °C,-80 °C
- Storage Comment
- Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
- Expiry Date
- 24 months
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- Target
- Integrin Alpha2b (CD41)
- Alternative Name
- ITGA2B (CD41 Products)
- Synonyms
- AI172977 antibody, CD41 antibody, CD41B antibody, GpIIb antibody, alphaIIb antibody, BDPLT16 antibody, BDPLT2 antibody, GP2B antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, integrin alpha 2b antibody, integrin subunit alpha 2b antibody, Itga2b antibody, ITGA2B antibody
- Background
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BDPLT16, BDPLT2, GPalpha IIb, GT, HPA3, Integrin alpha IIb, ITGA2B, ITGAB, platelet fibrinogen receptor, alpha subunit, platelet glycoprotein IIb of IIb/IIIa complex,CD41a / Integrin-b (Platelet Marker)
Cellular localisation: Cell Surface - Molecular Weight
- 90kDa
- Gene ID
- 3674, 411312
- UniProt
- P08514
- Pathways
- Integrin Complex
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