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Integrin Alpha2b antibody

CD41 Reactivity: Human FACS, IF Host: Mouse Monoclonal ITGA2B-1036 unconjugated
Catalog No. ABIN6937578
  • Target See all Integrin Alpha2b (CD41) Antibodies
    Integrin Alpha2b (CD41)
    Reactivity
    • 105
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    Human
    Host
    • 66
    • 41
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    Mouse
    Clonality
    • 82
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    Monoclonal
    Conjugate
    • 52
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    This Integrin Alpha2b antibody is un-conjugated
    Application
    • 93
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    Flow Cytometry (FACS), Immunofluorescence (IF)
    Specificity
    Reacts with a calcium-dependent complex of CD41/CD61, a dimer of 90 kDa and 140 kDa present on the membrane of normal platelets and megakaryocytes. CD41/CD61 is also known as platelet glycoprotein GPIIb/GPIIIa or integrin IIa/ 3. This complex is the receptor of fibrinogen, fibronectin and von Willebrand factor, and mediates platelet adhesion and aggregation.
    Cross-Reactivity (Details)
    Human.
    Purification
    1.0mg/ml of Ab purified from Bioreactor by Protein A/G.
    Immunogen
    Recombinant full-length human Integrin alpha IIb protein
    Clone
    ITGA2B-1036
    Isotype
    IgG1 kappa
    Top Product
    Discover our top product CD41 Primary Antibody
  • Application Notes

    Known_Application: Flow Cytometry (1-2 μg/million cells), Immunofluorescence (1-2 μg/mL), Optimal dilution for a specific application should be determined.

    Positive_Control: KG1a, HEL cells and human platelets in lymph nodes or tonsils.

    Restrictions
    For Research Use only
  • Concentration
    1.0 mg/mL
    Buffer
    Prepared in 10 mM PBS, WITHOUT BSA and Azide.
    Preservative
    Azide free
    Storage
    -20 °C,-80 °C
    Storage Comment
    Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.
    Expiry Date
    24 months
  • Target
    Integrin Alpha2b (CD41)
    Alternative Name
    ITGA2B (CD41 Products)
    Synonyms
    AI172977 antibody, CD41 antibody, CD41B antibody, GpIIb antibody, alphaIIb antibody, BDPLT16 antibody, BDPLT2 antibody, GP2B antibody, GPIIb antibody, GT antibody, GTA antibody, HPA3 antibody, integrin alpha 2b antibody, integrin subunit alpha 2b antibody, Itga2b antibody, ITGA2B antibody
    Background
    BDPLT16, BDPLT2, GPalpha IIb, GT, HPA3, Integrin alpha IIb, ITGA2B, ITGAB, platelet fibrinogen receptor, alpha subunit, platelet glycoprotein IIb of IIb/IIIa complex,CD41a / Integrin-b (Platelet Marker)
    Cellular localisation: Cell Surface
    Molecular Weight
    90kDa
    Gene ID
    3674, 411312
    UniProt
    P08514
    Pathways
    Integrin Complex
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