PAX7 antibody (AA 301-505)

Catalog No. ABIN6938124

Product Details anti-PAX7 Antibody

Target: PAX7 (Paired Box 7 (PAX7))

Binding Specificity: AA 301-505

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This PAX7 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunofluorescence (IF)

Specificity: The Pax gene family of nuclear transcription factors is comprised of nine members that function during embryogenesis to regulate the temporal and position-dependent differentiation of cells. In addition, the family is involved in a variety of signal transduction pathways in the adult organism. Mutations in the Pax family of proteins have been linked to disease and cancer in humans. Pax-7 is a protein specifically expressed in cultured satellite cell-derived myoblasts. In situ hybridization reveals that Pax-7 is also expressed in satellite cells residing in adult muscle. A chromosomal aberration in the gene encoding Pax-7 causes rhabdomyosarcoma 2 (RMS2) (also called alveolar rhabdomyosarcoma).

Cross-Reactivity (Details): Human. Mouse. Rat Chicken. Zebrafish.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Recombinant fragment (aa301-505) of human PAX7 protein (exact sequence is proprietary)

Clone: PAX7-497

Isotype: IgG1 kappa

Application Details

Application Notes:

Known_Application: Immunofluorescence (1-2 μg/mL), Flow Cytometry (1-2 μg/million cells), Western Blot (1-2 μg/mL), Optimal dilution for a specific application should be determined.

Positive_Control: HeLa, Jurkat, A431, MCF-7, U2OS or NIH/3T3 cells. Rhabdomyosarcoma (RMS).

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for PAX7

Target: PAX7 (Paired Box 7 (PAX7))

Alternative Name: PAX7 (PAX7 Products)

Synonyms: PAX7 antibody, HUP1 antibody, PAX7B antibody, RMS2 antibody, pax-7 antibody, PAX-7 antibody, RGD1564360 antibody, Pax-7 antibody, pax7 antibody, pax7c antibody, pax7d antibody, pax7e antibody, paired box 7 antibody, paired box protein Pax-7 antibody, paired box 7 L homeolog antibody, paired box 7a antibody, PAX7 antibody, pax7.L antibody, LOC536229 antibody, Pax7 antibody, pax7a antibody

Background: HUP1, Paired box gene 7, Paired box homeotic gene 7, Paired domain gene HuP1, PAX7 transcriptional factor, PAX7/FKHR fusion gene, PAX7B, RMS2,PAX7 (Rhabdomyosarcoma Marker)
Cellular localisation: Nuclear

Molecular Weight: 57kDa

Gene ID: 5081, 113253

UniProt: P23759