TNFRSF18 antibody

Catalog No. ABIN6938615

Product Details anti-TNFRSF18 Antibody

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Reactivity: Human

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNFRSF18 antibody is un-conjugated

Application: ELISA, Coating (Coat)

Specificity: The tumor necrosis factor receptor (TNFR) superfamily represents a growing family of type I transmembrane glycoproteins that are involved in various cellular functions, including proliferation, differentiation and programmed cell death. These proteins share homology for cysteine-rich repeats in the extracellular ligand binding domain and an intracellular death domain. Members of the TNFR superfamily transmit signals through protein-protein interactions, and these signals can lead to the activation of either the caspase and Jun kinase pathways, which promote cell death, or the NFB signaling pathway.

Cross-Reactivity (Details): Human.

Purification: 1.0mg/ml of Ab purified from Bioreactor by Protein A/G.

Immunogen: Human full-length TNFRSF18 protein

Clone: GITR-1585

Isotype: IgG3 kappa

Application Details

Application Notes:

Known_Application: ELISA (For coating, order Ab without BSA & Azide),Optimal dilution for a specific application should be determined.

Positive_Control: Jurkat cells.

Restrictions: For Research Use only

Handling

Concentration: 1.0 mg/mL

Buffer: Prepared in 10 mM PBS, WITHOUT BSA and Azide.

Preservative: Azide free

Storage: -20 °C,-80 °C

Storage Comment: Antibody without azide store at -20 to -80 °C. Antibody is stable for 24 months. Non-hazardous.

Expiry Date: 24 months

Target Details for TNFRSF18

Target: TNFRSF18 (Tumor Necrosis Factor Receptor Superfamily, Member 18 (TNFRSF18))

Alternative Name: TNFRSF18 (TNFRSF18 Products)

Synonyms: GITR antibody, TNFRSF18 antibody, AITR antibody, Gitr antibody, CD357 antibody, GITR-D antibody, TNF receptor superfamily member 18 antibody, tumor necrosis factor receptor superfamily, member 18 antibody, TNFRSF18 antibody, Tnfrsf18 antibody

Background: Activation inducible TNFR family receptor, AITR, GITRD, Glucocorticoid induced TNFR related protein, Glucocorticoid-induced TNFR-related protein, TNF receptor superfamily activation inducible protein, TNFRSF18,CD357 / GITR
Cellular localisation: Secreted and Cell Surface

Molecular Weight: 25kDa

Gene ID: 8784, 212680

UniProt: Q9Y5U5

Pathways: Cancer Immune Checkpoints