CYP1A1/2 antibody
-
- Target See all CYP1A1/2 Antibodies
- CYP1A1/2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1/2 (CYP1A1/2))
-
Reactivity
- Human, Rat, Mouse, Primate
-
Host
- Mouse
-
Clonality
- Monoclonal
-
Conjugate
- This CYP1A1/2 antibody is un-conjugated
-
Application
- Western Blotting (WB), Immunofluorescence (IF), Immunohistochemistry (IHC), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogen
- 3-methylcholanthrene induced rat cytochrome P450 protein.
- Clone
- MC1
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CYP1A1/2 Primary Antibody
-
-
- Application Notes
-
Positive Control: HeLa cells. Liver or Cardiac muscle.
Known Application: Immunofluorescence (0.5-1 μg/mL), Western Blot (0.5-1 μg/mL), Immunohistochemistry (Formalin-fixed) (0.25-0.5 μg/mL for 30 minutes at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
-
- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
-
- Target
- CYP1A1/2 (Cytochrome P450, Family 1, Subfamily A, Polypeptide 1/2 (CYP1A1/2))
- Alternative Name
- CYP1A1 / CYP1A2 (CYP1A1/2 Products)
- Synonyms
- CP12 antibody, Cyp1a1 antibody, P450-3 antibody, cytochrome P450, family 1, subfamily a, polypeptide 2 antibody, Cyp1a2 antibody
- Background
- Cytochrome P450 oxidase (commonly abbreviated CYP) is a generic term for a large number of related, but distinct, oxidative enzymes important in vertebrate physiology. The cytochrome P450 mixed-function monooxygenase system is probably the most important element of Phase I metabolism in mammals. P450s are membrane-bound, either in the inner membrane of mitochondria or in the endoplasmic reticulum of cells where they metabolise thousands of endogenous and exogenous compounds. In the liver, these substrates include toxins, drugs, and other unneeded and potentially harmful molecules. Humans have 18 families of cytochrome P450 genes and 43 subfamilies, the CYP1 family is involved in drug metabolism and includes 3 subfamilies, 3 genes and 1 pseudogene.
- Molecular Weight
- 58kDa
- Gene ID
- 1543, 1544
- UniProt
- P04798, P05177
-