CYP2E1 antibody (C-Term)
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- Target See all CYP2E1 Antibodies
- CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
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Binding Specificity
- C-Term
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Reactivity
- Human
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Host
- Mouse
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Clonality
- Monoclonal
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Conjugate
- This CYP2E1 antibody is un-conjugated
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Application
- Immunohistochemistry (IHC), Staining Methods (StM)
- Purification
- Purified by Protein A/G
- Immunogen
- Ovalbumin-conjugated synthetic peptide HIGFGCIPPR (C-terminal sequence)
- Clone
- M12P4H2
- Isotype
- IgG1 kappa
- Top Product
- Discover our top product CYP2E1 Primary Antibody
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- Application Notes
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Positive Control: HepG2 cells. Liver.
Known Application: Immunohistochemistry (Formalin-fixed) (0.1-0.2 μg/mL for 30 min at RT)(Staining of formalin-fixed tissues requires boiling tissue sections in 10 mM citrate buffer, pH 6.0, for 10-20 min followed by cooling at RT for 20 minutes)Optimal dilution for a specific application should be determined.
- Restrictions
- For Research Use only
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- Concentration
- 200 μg/mL
- Buffer
- 10 mM PBS with 0.05 % BSA & 0.05 % azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- 4 °C,-80 °C
- Storage Comment
- Antibody with azide - store at 2 to 8°C. Antibody without azide - store at -20 to -80°C. Antibody is stable for 24 months. Non-hazardous. No MSDS required.
- Expiry Date
- 24 months
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- Target
- CYP2E1 (Cytochrome P450, Family 2, Subfamily E, Polypeptide 1 (CYP2E1))
- Alternative Name
- CYP2E1 (CYP2E1 Products)
- Synonyms
- CYP2E1 antibody, CYP2E antibody, CYPIIE1 antibody, CPE1 antibody, P450-J antibody, P450C2E antibody, Cyp2e antibody, cytochrome P450, family 2, subfamily E, polypeptide 1 antibody, cytochrome P450 2E1 antibody, cytochrome P450 2E1-like antibody, cytochrome P450 family 2 subfamily E member 1 antibody, cytochrome P450, family 2, subfamily e, polypeptide 1 antibody, CYP2E1 antibody, PTRG_07411 antibody, LOC100342572 antibody, LOC100727914 antibody, LOC101843716 antibody, Cyp2e1 antibody
- Background
- This gene encodes a member of the cytochrome P450 superfamily of enzymes. The cytochrome P450 proteins are monooxygenases, which catalyze many reactions involved in drug metabolism and synthesis of cholesterol, steroids and other lipids. This protein localizes to the endoplasmic reticulum and is induced by ethanol, the diabetic state, and starvation. The enzyme metabolizes both endogenous substrates, such as ethanol, acetone, and acetal, as well as exogenous substrates including benzene, carbon tetrachloride, ethylene glycol, and nitrosamines, which are pre-mutagens found in cigarette smoke. Due to its many substrates, this enzyme may be involved in such varied processes as gluconeogenesis, hepatic cirrhosis, diabetes, and cancer.
- Molecular Weight
- ~50-55kDa
- Gene ID
- 1571
- UniProt
- P05181
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