Recombinant Bcl-2 antibody (AA 1-200)
Quick Overview for Recombinant Bcl-2 antibody (AA 1-200) (ABIN6942240)
Target
See all Bcl-2 (BCL2) AntibodiesAntibody Type
Reactivity
Host
Clonality
Conjugate
Application
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Binding Specificity
- AA 1-200
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Purpose
- Bcl-2 Recombinant Antibody
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Cross-Reactivity
- Human
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Purification
- Purified by Protein A.
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Immunogen
- Recombinant human Bcl-2 between 1 to 200 amino acids.
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Isotype
- IgG
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Application Notes
- WB(1:300-5000)
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Restrictions
- For Research Use only
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Format
- Liquid
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Concentration
- Lot specific
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Buffer
- 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol
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Preservative
- ProClin
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Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
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Storage
- 4 °C,-20 °C
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Storage Comment
- Shipped at 4°. Store at -20°C for one year. Avoid repeated freeze/thaw cycles.
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Expiry Date
- 12 months
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- Bcl-2 (BCL2) (B-Cell CLL/lymphoma 2 (BCL2))
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Alternative Name
- BCL2
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Background
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Synonyms: Apoptosis regulator Bcl-2, BCL2
Background: Suppresses apoptosis in a variety of cell systems including factor-dependent lymphohematopoietic and neural cells. Regulates cell death by controlling the mitochondrial membrane permeability. Appears to function in a feedback loop system with caspases. Inhibits caspase activity either by preventing the release of cytochrome c from the mitochondria and/or by binding to the apoptosis-activating factor (APAF-1).
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Gene ID
- 596
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UniProt
- P10415
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Pathways
- MAPK Signaling, PI3K-Akt Signaling, Apoptosis, Caspase Cascade in Apoptosis, Regulation of Muscle Cell Differentiation, Cell-Cell Junction Organization, Skeletal Muscle Fiber Development, Autophagy, Smooth Muscle Cell Migration, Negative Regulation of intrinsic apoptotic Signaling
Target
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