Gephyrin antibody

Catalog No. ABIN6943530

Product Details anti-Gephyrin Antibody

Target: Gephyrin (GPHN)

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Gephyrin antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Recombinant protein within human Gephyrin aa 1-100.

Clone: 7A1

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Gephyrin

Target: Gephyrin (GPHN)

Alternative Name: Gephyrin (GPHN Products)

Synonyms: 5730552E08Rik antibody, AI662856 antibody, BC027112 antibody, C230040D23 antibody, GPH antibody, GPHRYN antibody, geph antibody, Geph antibody, GPHN antibody, GEPH antibody, HKPX1 antibody, gpgb1 antibody, DKFZp459M0825 antibody, gephyrin antibody, gephyrin L homeolog antibody, gephyrin a antibody, Gphn antibody, GPHN antibody, gphn.L antibody, gphna antibody, PTRG_08978 antibody, VDBG_00775 antibody, Tsp_03043 antibody, gphn antibody

Background:

Synonyms: Gephyrin, Molybdopterin adenylyltransferase, Domain G, Molybdopterin molybdenumtransferase, Domain E, MPT adenylyltransferase, MPT Mo-transferase, GPHN, GPH, KIAA1385

Background: The sub-membraneous region at the postsynaptic membrane contains a number of proteins critical for receptor targeting. Gephyrin is a microtubule-associated protein highly expressed in brain and localized to neuronal postsynaptic membranes. Gephyrin is essential for the postsynaptic localization of the inhibitory glycine receptor and is thought to anchor the receptor to subsynaptic microtubules. The protein is expressed in most mammalian tissues with predominant expression in brain. At least five additional splice variants of Gephyrin ranging in molecular weight have been identified in rat and human brain tissue.

Gene ID: 10243

UniProt: Q9NQX3

Pathways: Synaptic Membrane, Skeletal Muscle Fiber Development