Nucleostemin antibody

Catalog No. ABIN6943564

Product Details anti-Nucleostemin Antibody

Target: Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This Nucleostemin antibody is un-conjugated

Application: Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Recombinant protein corresponding to the C-terminus of human Nucleostemin.

Clone: 6H5

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for Nucleostemin

Target: Nucleostemin (GNL3) (Guanine Nucleotide Binding Protein-Like 3 (Nucleolar) (GNL3))

Alternative Name: GNL3 (GNL3 Products)

Synonyms: id:ibd2914 antibody, nstm antibody, wu:fb38a04 antibody, wu:fc55d07 antibody, zgc:123093 antibody, e2ig3 antibody, C77032 antibody, E2IG3 antibody, NNP47 antibody, NS antibody, BC037996 antibody, Ns antibody, guanine nucleotide binding protein-like 3 (nucleolar) antibody, G protein nucleolar 3 antibody, guanine nucleotide binding protein-like 3 (nucleolar) L homeolog antibody, gnl3 antibody, GNL3 antibody, Gnl3 antibody, gnl3.L antibody

Background:

Synonyms: Guanine nucleotide-binding protein-like 3, E2-induced gene 3 protein, Novel nucleolar protein 47, Nucleolar GTP-binding protein 3, Nucleostemin, NNP47, GNL3, E2IG3,

Background: May be required to maintain the proliferative capacity of stem cells. Stabilizes MDM2 by preventing its ubiquitination, and hence proteasomal degradation. May interact with p53 and may be involved in tumorigenesis. This protein is found in both the nucleus and nucleolus. Three transcript variants encoding two different isoforms have been found for this gene

Gene ID: 26354

UniProt: Q9BVP2