HNRNPA1 antibody

Catalog No. ABIN6943685

Product Details anti-HNRNPA1 Antibody

Target: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This HNRNPA1 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Human hnRNP A1 aa 300 to the C-terminus

Clone: 4H7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for HNRNPA1

Target: HNRNPA1 (Heterogeneous Nuclear Ribonucleoprotein A1 (HNRNPA1))

Alternative Name: hnRNP A1 (HNRNPA1 Products)

Synonyms: HNRPA1 antibody, HNRPA1L3 antibody, hnRNP A1 antibody, hnRNP-A1 antibody, hnrpa1 antibody, TPT1P antibody, HNRNPA1 antibody, D15Ertd119e antibody, Hdp antibody, Hnrpa1 antibody, hnrnp-A1 antibody, ROA1 antibody, zgc:66127 antibody, heterogeneous nuclear ribonucleoprotein A1 antibody, heterogeneous nuclear ribonucleoprotein A1b antibody, Heterogeneous nuclear ribonucleoprotein A1 antibody, heterogeneous nuclear ribonucleoprotein A1 S homeolog antibody, ribonucleoprotein A1a antibody, heterogeneous nuclear ribonucleoprotein A1-like antibody, heterogeneous nuclear ribonucleoprotein A1a antibody, HNRNPA1 antibody, hnrnpa1b antibody, LOC100101226 antibody, roa1 antibody, Hnrnpa1 antibody, hnrnpa1.S antibody, hnrnpa1 antibody, LOC100359118 antibody, hnrnpa1a antibody

Background:

Synonyms: Heterogeneous nuclear ribonucleoprotein A1, Helix-destabilizing protein, Single-strand RNA-binding protein, hnRNP core protein A1, Heterogeneous nuclear ribonucleoprotein A1, N-terminally processed, HNRNPA1, HNRPA1

Background: Heterogeneous nuclear ribonucleoproteins (hnRNPs) constitute a set of poly-peptides that contribute to mRNA transcription and pre-mRNA processing as well as mature mRNA transport to the cytoplasm and translation. They also bind heterogeneous nuclear RNA (hnRNA), which are the transcripts produced by RNA polymerase II. There are approximately 20 known hnRNP proteins, and their complexes are the major constituents of the spliceosome. The majority of hnRNP protein components are localized to the nucleus, however some shuttle between the nucleus and the cytoplasm. The A/B subfamily of hnRNPs include A1, A2/B1, A3 and A0, and in Xenopus, hnRNP A1, A2 and A3 are ubiquitously expressed throughout development as well as in adult tissues. hnRNP A1 and A2/B1 regulate the processing of pre-mRNA by directly antagonizing the association of various splicing factors and by influencing the splice site selection on pre-mRNA. The hnRNP A0 gene is distinct from the other A/B family members, and it encodes a low-abundance protein, which is implicated in mRNA stability.

Gene ID: 3178

UniProt: P09651