Recombinant IL-1 beta antibody (C-Term)

Catalog No. ABIN6943799

The Rabbit Monoclonal anti-IL-1 beta antibody (ABIN6943799) specifically detects IL-1 beta in WB. The antibody is reactive with Human samples.

Quick Overview for Recombinant IL-1 beta antibody (C-Term) (ABIN6943799)

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Antibody Type: Recombinant Antibody

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This IL-1 beta antibody is un-conjugated

Application: Western Blotting (WB)

Product Details anti-IL-1 beta Antibody

Binding Specificity: C-Term

Purpose: IL-1 beta Recombinant Antibody

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Recombinant protein within Human IL1 beta aa 100 to the C-terminus

Isotype: IgG

Application Details

Application Notes: WB(WB(1:1000-5000))

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: 0.01M TBS ( pH 7.4), 1 % BSA, 0.02 % Proclin 300, and 50 % Glycerol

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for IL-1 beta

Target: IL-1 beta (IL1B) (Interleukin 1, beta (IL1B))

Alternative Name: IL1B

Background:

Synonyms: Interleukin-1 beta, Catabolin, IL-1 beta, IL1B, IL1F2, IL1-BETA.

Background: Produced by activated macrophages, IL-1 stimulates thymocyte proliferation by inducing IL-2 release, B-cell maturation and proliferation, and fibroblast growth factor activity. IL-1 proteins are involved in the inflammatory response, being identified as endogenous pyrogens, and are reported to stimulate the release of prostaglandin and collagenase from synovial cells.

Gene ID: 3553

UniProt: P01584

Pathways: NF-kappaB Signaling, Interferon-gamma Pathway, TLR Signaling, Negative Regulation of Hormone Secretion, Cellular Response to Molecule of Bacterial Origin, Carbohydrate Homeostasis, Glycosaminoglycan Metabolic Process, Myometrial Relaxation and Contraction, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Autophagy, Cancer Immune Checkpoints, Inflammasome