NDUFS3 antibody

Catalog No. ABIN6944233

Product Details anti-NDUFS3 Antibody

Target: NDUFS3 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 3, 30kDa (NADH-Coenzyme Q Reductase) (NDUFS3))

Reactivity: Human

Host: Rabbit

Clonality: Monoclonal

Conjugate: This NDUFS3 antibody is un-conjugated

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human

Purification: Purified by Protein A.

Immunogen: Recombinant protein within human NDUFS3 aa 100 to the C-terminus

Clone: 9B7

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for NDUFS3

Target: NDUFS3 (NADH Dehydrogenase (Ubiquinone) Fe-S Protein 3, 30kDa (NADH-Coenzyme Q Reductase) (NDUFS3))

Alternative Name: NDUFS3 (NDUFS3 Products)

Synonyms: CI-30 antibody, 0610010M09Rik antibody, CI-30kD antibody, GB15355 antibody, zgc:112520 antibody, NADH:ubiquinone oxidoreductase core subunit S3 antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 3 antibody, NADH dehydrogenase [ubiquinone] iron-sulfur protein 3, mitochondrial antibody, NADH:ubiquinone oxidoreductase core subunit S3 S homeolog antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 3, (NADH-coenzyme Q reductase) antibody, NADH dehydrogenase (ubiquinone) Fe-S protein 3, 30kDa (NADH-coenzyme Q reductase) antibody, NDUFS3 antibody, Ndufs3 antibody, ndufs3 antibody, LOC411411 antibody, ndufs3.S antibody, LOC100228726 antibody

Background:

Synonyms: NADH dehydrogenase [ubiquinone] iron-sulfur protein 3 mitochondrial, Complex I-30kD, NADH-ubiquinone oxidoreductase 30 kDa subunit, CI-30kD, NDUFS3, MC1DN8, NADH:ubiquinone oxidoreductase core subunit S3.

Background: This gene encodes one of the iron-sulfur protein (IP) components of mitochondrial NADH:ubiquinone oxidoreductase (complex I). Mutations in this gene are associated with Leigh syndrome resulting from mitochondrial complex I deficiency. NDUFS3 is the core subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I) that is believed to belong to the minimal assembly required for catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone.

Gene ID: 4722

UniProt: O75489

Pathways: Negative Regulation of intrinsic apoptotic Signaling