PDCD4 antibody
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- Target See all PDCD4 Antibodies
- PDCD4 (Programmed Cell Death 4 (PDCD4))
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Reactivity
- Human, Mouse
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Host
- Rabbit
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Clonality
- Monoclonal
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Conjugate
- This PDCD4 antibody is un-conjugated
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Application
- Western Blotting (WB), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p)), Flow Cytometry (FACS)
- Cross-Reactivity
- Human, Mouse
- Purification
- Purified by Protein A.
- Immunogen
- Full length protein
- Clone
- 3G1
- Isotype
- IgG
- Top Product
- Discover our top product PDCD4 Primary Antibody
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- Application Notes
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WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400
IF(IHC-P) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store for 1 year at -20°C from date of shipment.
- Expiry Date
- 12 months
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- Target
- PDCD4 (Programmed Cell Death 4 (PDCD4))
- Alternative Name
- PDCD4 (PDCD4 Products)
- Synonyms
- H731 antibody, D19Ucla1 antibody, Ma3 antibody, Tis antibody, Dug antibody, cb45 antibody, pdcd4 antibody, sb:cb45 antibody, wu:fc84b08 antibody, h731 antibody, MGC69337 antibody, PDCD4 antibody, wu:fa55g03 antibody, wu:fb08a11 antibody, wu:fe01a02 antibody, zgc:66311 antibody, programmed cell death 4 antibody, programmed cell death 4b antibody, programmed cell death 4 L homeolog antibody, programmed cell death 4 (neoplastic transformation inhibitor) antibody, programmed cell death 4a antibody, PDCD4 antibody, Pdcd4 antibody, pdcd4b antibody, pdcd4.L antibody, pdcd4 antibody, pdcd4a antibody
- Background
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Synonyms: Programmed cell death protein 4, Neoplastic transformation inhibitor protein, Nuclear antigen H731-like, Protein 197/15a, PDCD4, H731
Background: Inhibits translation initiation and cap-dependent translation. May excert its function by hindering the interaction between EIF4A1 and EIF4G. Inhibits the helicase activity of EIF4A. Modulates the activation of JUN kinase. Down-regulates the expression of MAP4K1, thus inhibiting events important in driving invasion, namely, MAPK85 activation and consequent JUN-dependent transcription. May play a role in apoptosis. Tumor suppressor. Inhibits tumor promoter-induced neoplastic transformation. Binds RNA (By similarity).
- Gene ID
- 27250
- UniProt
- Q53EL6
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