PTGES3 antibody

Catalog No. ABIN6944714

Product Details anti-PTGES3 Antibody

Target: PTGES3 (Prostaglandin E Synthase 3 (Cytosolic) (PTGES3))

Reactivity: Human, Rat, Mouse

Host: Rabbit

Clonality: Monoclonal

Conjugate: This PTGES3 antibody is un-conjugated

Application: Western Blotting (WB), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunoprecipitation (IP), Immunofluorescence (Cultured Cells) (IF (cc))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Synthetic peptide within human p23 aa 50-100

Clone: 1A26

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IP(1-2 μg)
IHC()

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store at 4°C for up to 2 weeks. For long term storage, store at -20°C in small aliquots to prevent freeze-thaw cycles.

Expiry Date: 12 months

Target Details for PTGES3

Target: PTGES3 (Prostaglandin E Synthase 3 (Cytosolic) (PTGES3))

Alternative Name: PTGES3 (PTGES3 Products)

Synonyms: P23 antibody, TEBP antibody, cPGES antibody, PTGES3 antibody, 5730442A20Rik antibody, Ptges antibody, Tebp antibody, p23 antibody, sid3177 antibody, RGD1561913 antibody, CPGES antibody, cPGES-1 antibody, ptges3 antibody, wu:fb98d06 antibody, zgc:65804 antibody, zgc:77131 antibody, tebp antibody, wu:fb50a04 antibody, zgc:86751 antibody, prostaglandin E synthase 3 antibody, prostaglandin E synthase 3 (cytosolic) pseudogene antibody, prostaglandin E synthase 3a (cytosolic) antibody, prostaglandin E synthase 3 L homeolog antibody, prostaglandin E synthase 3b (cytosolic) antibody, PTGES3 antibody, LOC743066 antibody, Ptges3 antibody, ptges3a antibody, ptges3.L antibody, ptges3b antibody

Background:

Synonyms: Prostaglandin E synthase 3, Cytosolic prostaglandin E2 synthase, Hsp90 co-chaperone, Progesterone receptor complex p23, Telomerase-binding protein p23, cPGES, P23, TEBP.

Background: Cytosolic prostaglandin synthase that catalyzes the oxidoreduction of prostaglandin endoperoxide H2 (PGH2) to prostaglandin E2 (PGE2). Molecular chaperone that localizes to genomic response elements in a hormone-dependent manner and disrupts receptor-mediated transcriptional activation, by promoting disassembly of transcriptional regulatory complexes. Facilitates HIF alpha proteins hydroxylation via interaction with EGLN1/PHD2, leading to recruit EGLN1/PHD2 to the HSP90 pathway.

Gene ID: 10728

UniProt: Q15185

Pathways: Intracellular Steroid Hormone Receptor Signaling Pathway, Cellular Glucan Metabolic Process