RCAS1 antibody (AA 151-213) (Biotin)

Catalog No. ABIN6944760

Product Details anti-RCAS1 Antibody (Biotin)

Target: RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))

Binding Specificity: AA 151-213

Reactivity: Mouse

Host: Rabbit

Clonality: Polyclonal

Conjugate: This RCAS1 antibody is conjugated to Biotin

Application: ELISA, Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Immunohistochemistry (Frozen Sections) (IHC (fro))

Cross-Reactivity: Mouse

Predicted Reactivity: Human,Cow,Pig,Chicken,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human RCAS1

Isotype: IgG

Application Details

Application Notes: IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for RCAS1

Target: RCAS1 (EBAG9) (Estrogen Receptor Binding Site Associated, Antigen, 9 (EBAG9))

Alternative Name: RCAS1/EBAG9 (EBAG9 Products)

Synonyms: EB9 antibody, PDAF antibody, MGC56608 antibody, zgc:56608 antibody, MGC84425 antibody, EBAG9 antibody, AI835379 antibody, Rcas1 antibody, RCAS1 antibody, eb9 antibody, pdaf antibody, rcas1 antibody, estrogen receptor binding site associated, antigen, 9 antibody, estrogen receptor binding site associated, antigen, 9 L homeolog antibody, estrogen receptor-binding fragment-associated gene 9 antibody, EBAG9 antibody, ebag9 antibody, ebag9.L antibody, Ebag9 antibody

Background:

Synonyms: BAG9, Cancer associated surface antigen, Cancer associated surface antigen RCAS1, EB9, EBAG 9, Estrogen receptor binding fragment associated gene 9 protein, Estrogen receptor binding site associated antigen 9, PDAF, RCAS 1, RCAS1, Receptor binding cancer antigen expressed on SiSo cells.

Background: This gene was identified as an estrogen-responsive gene. Regulation of transcription by estrogen is mediated by estrogen receptor, which binds to the estrogen-responsive element found in the 5'-flanking region of this gene. The encoded protein is a tumor-associated antigen that is expressed at high frequency in a variety of cancers. This gene may also participate in the suppression of cell proliferation and inducing apoptotic cell death through activation of interleukin-1-beta converting enzyme (ICE)-like proteases. Alternate splicing results in multiple transcript variants. A pseudogene of this gene has been defined on chromosome 10.

Gene ID: 9166

UniProt: O00559