Fc epsilon RI/FCER1A antibody
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- Target See all Fc epsilon RI/FCER1A (FCER1A) Antibodies
- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
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Reactivity
- Mouse
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Host
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Armenian Hamster
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Clonality
- Monoclonal
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Conjugate
- This Fc epsilon RI/FCER1A antibody is un-conjugated
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Application
- Flow Cytometry (FACS), Immunohistochemistry (IHC), Immunoprecipitation (IP), Functional Studies (Func)
- Purification
- This monoclonal antibody preparation was purified from tissue culture supernatant via affinity chromatography. For In Vivo Ready™ (IVR) products, each preparation is also evaluated for endotoxin levels using the LAL assay. It is recommended to store the product undiluted at 4°C. Do not freeze.
- Endotoxin Level
- Low endotoxin: < 0.01 EU/ug
- Clone
- MAR-1
- Isotype
- IgG
- Top Product
- Discover our top product FCER1A Primary Antibody
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- Application Notes
- This purified format is guaranteed to be >90 % pure as determined by SDS-PAGE analysis.
- Comment
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2 mg/mL
- Restrictions
- For Research Use only
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- Buffer
- 10 mM NaH2PO4, 150 mM NaCl, pH 7.2
- Preservative
- Azide free
- Storage
- 4 °C
- Storage Comment
- 2-8°C
- Expiry Date
- 12 months
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- Target
- Fc epsilon RI/FCER1A (FCER1A) (Fc Fragment of IgE Receptor Ia (FCER1A))
- Alternative Name
- FceR1 (FCER1A Products)
- Synonyms
- FCER1A antibody, FCE1A antibody, FcERI antibody, Iger01 antibody, RATIGER01 antibody, Fce1a antibody, Fcr-5 antibody, fcepsilonri antibody, Fc fragment of IgE receptor Ia antibody, Fc receptor, IgE, high affinity I, alpha polypeptide antibody, FCER1A antibody, Fcer1a antibody
- Background
- The MAR-1 antibody reacts with the Fc epsilon Receptor I alpha chain (FceRIa), a transmembrane protein member of the Ig superfam- ily. This chain, together with a beta chain and two gamma chains form a tetrameric complex that supports IgE-mediated signaling and subsequent release of chemical mediators of allergy and immediate hypersensitivity. FceR1a is upregulated in the presence of IgE on those cell types which express it, such as Mast cells and Basophils.The MAR-1 antibody is widely used both in flow cytometry and for depletion of cells in vitro / in vivo.
- Gene ID
- 2205
- UniProt
- P20489
- Pathways
- Fc-epsilon Receptor Signaling Pathway, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process
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