IL-2 antibody

Catalog No. ABIN6963853

Cited in 5+ publications. The Rat Monoclonal anti-IL-2 antibody (Clone 1A12) (ABIN6963853) specifically detects IL-2 in ELISA and ELISpot. The antibody is reactive with Mouse samples.

Quick Overview for IL-2 antibody (ABIN6963853)

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Reactivity: Mouse

Host: Rat

Clonality: Monoclonal

Conjugate: This IL-2 antibody is un-conjugated

Application: ELISA, ELISpot

Clone: 1A12

Product Details anti-IL-2 Antibody

Specificity: Native and recombinant mouse IL-2

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Sterility: 0.2 μm filtered

Immunogen: Recombinant mouse IL-2

Isotype: IgG2a

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 mg/mL

Buffer: supplied at 1 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-IL-2 antibody (ABIN6963853)

Harmon, Spengler, Coleman-McCray, Nichol, Spiropoulou, McElroy: "CD4 T Cells, CD8 T Cells, and Monocytes Coordinate To Prevent Rift Valley Fever Virus Encephalitis." in: Journal of virology, Vol. 92, Issue 24, (2019) (PubMed).

Gai, Zheng, Wang, Wang, Zhao, Wang, Wong, Zhang, Feng, Qiu, Chi, Li, Wang, Gao, Shan, Yang, Xia: "Marburg virus-like particles by co-expression of glycoprotein and matrix protein in insect cells induces immune responses in mice." in: Virology journal, Vol. 14, Issue 1, pp. 204, (2018) (PubMed).

Ashrafi, Shapouri, Shirkhani, Mahdavi: "Anti-tumor effects of propranolol: Adjuvant activity on a transplanted murine breast cancer model." in: Biomedicine & pharmacotherapy, Vol. 104, pp. 45-51, (2018) (PubMed).

Yau, Piehl, Olsson, Holmdahl: "Effects of C2ta genetic polymorphisms on MHC class II expression and autoimmune diseases." in: Immunology, Vol. 150, Issue 4, pp. 408-417, (2017) (PubMed).

Tadepalli, Singh, Balakrishna, Murali, Batra: "Immunogenicity and protective efficacy of Brucella abortus recombinant protein cocktail (rOmp19+rP39) against B. abortus 544 and B. melitensis 16M infection in murine model." in: Molecular immunology, Vol. 71, pp. 34-41, (2016) (PubMed).

Target Details for IL-2

Target: IL-2 (IL2) (Interleukin 2 (IL2))

Alternative Name: IL2

Gene ID: 16183

Pathways: JAK-STAT Signaling, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Activated T Cell Proliferation