TNF alpha antibody

Catalog No. ABIN6963903

There is 1 publication for this product available. The Mouse Monoclonal anti-TNF alpha antibody is suitable to detect TNF alpha in samples from Non-Human Primate. It has been validated for ELISA and ELISpot.

Quick Overview for TNF alpha antibody (ABIN6963903)

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Reactivity: Non-Human Primate

Host: Mouse

Clonality: Monoclonal

Conjugate: This TNF alpha antibody is un-conjugated

Application: ELISA, ELISpot

Clone: MT21A8

Product Details anti-TNF alpha Antibody

Specificity: Native and recombinant TNF-α

Cross-Reactivity (Details): The monoclonal antibody reacts with human TNF-α and cross-react with TNF-α from non-human primates.

Purification: Purified from in vitro cultures by protein G affinity chromatography.

Sterility: 0.2 μm filtered

Immunogen: Recombinant human TNF-alpha

Isotype: IgG1

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 0.5 mg/mL

Buffer: supplied at 0.5 mg/mL in PBS with 0.02 % sodium azide

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: 4 °C,-20 °C

Storage Comment: Store product at 4-8°C or frozen at -20°C or below. Avoid repeated freezing/ thawing.

Expiry Date: 18 months

References for anti-TNF alpha antibody (ABIN6963903)

Phuah, Wong, Gideon, Maiello, Coleman, Hendricks, Ruden, Cirrincione, Chan, Lin, Flynn: "Effects of B Cell Depletion on Early Mycobacterium tuberculosis Infection in Cynomolgus Macaques." in: Infection and immunity, Vol. 84, Issue 5, pp. 1301-1311, (2017) (PubMed).

Target Details for TNF alpha

Target: TNF alpha (Tumor Necrosis Factor alpha (TNF alpha))

Alternative Name: TNFA

Gene ID: 7124

Pathways: NF-kappaB Signaling, Apoptosis, Caspase Cascade in Apoptosis, TLR Signaling, Cellular Response to Molecule of Bacterial Origin, Regulation of Leukocyte Mediated Immunity, Positive Regulation of Immune Effector Process, Production of Molecular Mediator of Immune Response, Positive Regulation of Endopeptidase Activity, Hepatitis C, Protein targeting to Nucleus, Inflammasome