NK2 Homeobox 5 antibody (N-Term)

Catalog No. ABIN6972433

Product Details anti-NK2 Homeobox 5 Antibody

Target: NK2 Homeobox 5 (NKX2-5)

Binding Specificity: N-Term

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This NK2 Homeobox 5 antibody is un-conjugated

Application: Western Blotting (WB)

Characteristics: The NKX2.5 (NK2 homeobox 5, CSX, Homeobox protein CSX, NKX2E, Homeobox protein NK-2 homolog E, NK2 transcription factor related, locus 5, CHNG5, cardiac-specific homeobox 1) gene encodes a homeobox-containing transcription factor that functions in heart formation and development. Alternative splicing results in multiple transcript variants. Implicated in commitment to and/or differentiation of the myocardial lineage. Acts as a transcriptional activator of ANF in cooperation with GATA4. Also interacts with JARID2 which represses its ability to activate transcription of ANF. NKX2.5 antibody (pAb) was raised in a Rabbit host. It has been validated for use in Western blot, it has been shown to react with Human samples.

Purification: Affinity Purified

Immunogen: This NKX2.5 antibody was raised against a peptide within the N-terminal region of human NKX2.5.

Isotype: IgG

Application Details

Application Notes: Optimal working dilution should be determined by the investigator.

Restrictions: For Research Use only

Handling

Buffer: Purified IgG in PBS with 30 % glycerol and 0.035 % sodium azide.

Preservative: Sodium azide

Precaution of Use: This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.

Target Details for NK2 Homeobox 5

Target: NK2 Homeobox 5 (NKX2-5)

Alternative Name: NKX2.5 (NKX2-5 Products)

Synonyms: CHNG5 antibody, CSX antibody, CSX1 antibody, HLHS2 antibody, NKX2.5 antibody, NKX2E antibody, NKX4-1 antibody, VSD3 antibody, Csx antibody, Nkx-2.5 antibody, Nkx2.5 antibody, tinman antibody, nk2.5 antibody, nkx2-5 antibody, zgc:111912 antibody, AR2 antibody, XNkx2-5 antibody, csx antibody, nkx-2.5 antibody, nkx2-5b antibody, nkx2.5 antibody, NKX2-5 antibody, Nkx2-5 antibody, csx1 antibody, nkx2e antibody, XNkx-2.5 antibody, CNKX-2.5 antibody, NKX-2.5 antibody, NK2 homeobox 5 antibody, NK2 homeobox 5 S homeolog antibody, NKX2-5 antibody, Nkx2-5 antibody, nkx2.5 antibody, nkx2-5.S antibody, nkx2-5 antibody

Molecular Weight: 35 kDa

NCBI Accession: NP_004378

Pathways: Regulation of Muscle Cell Differentiation, Skeletal Muscle Fiber Development