Recombinant SARS-CoV-2 Spike IgG/IgM antibody
Reactivity: SARS Coronavirus-2 (SARS-CoV-2)
ELISA
Host: Human
Monoclonal
AM043105 (105-43)
unconjugated
Recombinant Antibody
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- Target
- SARS-CoV-2 Spike IgG/IgM
- Antibody Type
- Recombinant Antibody
- Reactivity
- SARS Coronavirus-2 (SARS-CoV-2)
- Host
-
Human
- Clonality
- Monoclonal
- Application
- ELISA
- Characteristics
- COVID-19, which is short for coronavirus disease 2019, is the official name of the respiratory disease caused by infection with the novel coronavirus SARS-CoV-2. The virus that causes COVID-19 was named SARS-CoV-2 because it is a coronavirus genetically similar to, yet distinct from, the virus that caused the severe acute respiratory syndrome (SARS) outbreak in 2003. Studying the details of how this virus replicates and causes the disease will allow scientists and physicians to more rapidly develop fast and accurate methods of detection as well as to deploy therapeutic and vaccine strategies. This antibody was derived from COVID-19 patients who have cleared the virus. Patient serum IgG was sequenced and expressed as a chimeric full-length human immunoglobulin in mammalian 293 cells. This chimeric antibody contains a heavy chain CH1 that is IgG1 isotype, whereas its CH2/CH3/CH4 regions are IgM isotype. The antibody contains a Flag Tag and an 8X His Tag at the C-terminus. SARS-CoV-2 Spike IgG/IgM Antibody (AM5) (Clone AM5 (105-43)) was raised in a Human host. It has been validated for use in ELISA, it has been shown to react with Virus samples.
- Purification
- Ni-NTA
- Immunogen
- Derived from COVID-19 patients who have cleared the virus. Their antibodies were screened for reactivity to SARS-CoV-2 and then sequenced and expressed as recombinant antibodies.
- Clone
- AM043105 (105-43)
- Isotype
- IgG, IgM
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- Application Notes
- Optimal working dilution should be determined by the investigator.
- Restrictions
- For Research Use only
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- Buffer
- PBS, 30 % glycerol, 0.035 % sodium azide.
- Preservative
- Sodium azide
- Precaution of Use
- This product contains Sodium azide: a POISONOUS AND HAZARDOUS SUBSTANCE which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Avoid repeated freeze/thaw cycles by aliquoting items into single-use fractions for storage at -20°C for up to 2 years. Keep all reagents on ice when not in storage.
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- Target
- SARS-CoV-2 Spike IgG/IgM
- Target Type
- Antibody
- Molecular Weight
- 141 kDa (full length S1 protein)
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