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PD-L1 antibody (AA 31-130) (Alexa Fluor 350)

PD-L1 Reactivity: Mouse WB, IF (cc), IF (p) Host: Rabbit Polyclonal Alexa Fluor 350

Catalog No. ABIN6977044

Datasheet as PDF

Target See all PD-L1 Antibodies

PD-L1 (CD274 (PD-L1))
Binding Specificity
29

16

14

13

11

11

9

7

7

5

4

3

2

2

2

2

2

1

1

1

1

1

1

1

1

1

1

1
AA 31-130
Reactivity
168

105

63

7

6

5

5

1

1
Mouse
Host
126

59

15

4

4

1
Rabbit
Compatible Secondaries
Clonality
107

100

2
Polyclonal
Conjugate
98

14

13

11

8

5

5

5

5

5

5

5

4

4

4

4

3

3

3

2

1

1

1
This PD-L1 antibody is conjugated to Alexa Fluor 350
Application
137

102

60

39

37

27

17

16

16

15

10

7

5

4

3

3

2

2

1

1

1

1

1

1

1
Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity

Mouse

Predicted Reactivity

Rat

Purification

Purified by Protein A.

Immunogen

KLH conjugated synthetic peptide derived from mouse PD-L1

Isotype

IgG

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anti-CD274 (PD-L1) (C-Term) antibody
Verified PD-L1 Reactivity: Human WB, FACS, ELISA, IF Host: Goat Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 Reactivity: Human WB, FACS, IHC, ELISA, IF Host: Mouse Monoclonal 9B5F4 unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 Reactivity: Human WB, FACS, IHC, ELISA, ICC, Neut Host: Mouse Monoclonal 6D9A2 unconjugated

anti-CD274 (PD-L1) (AA 39-191) antibody
PD-L1 Reactivity: Human, Mouse WB, FACS, IHC, ELISA, IF, Coat, StM Host: Mouse Monoclonal PDL1-2746 unconjugated

anti-CD274 (PD-L1) (AA 48-290) antibody
PD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (Extracellular Domain) antibody
PD-L1 Reactivity: Human IHC Host: Rabbit Monoclonal unconjugated

anti-CD274 (PD-L1) (AA 34-241) antibody
PD-L1 Reactivity: Mouse WB, IHC, IP, ICC Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 24-153) antibody
PD-L1 Reactivity: Human WB, FACS, IHC, ELISA, ICC Host: Mouse Monoclonal 7D2A10 unconjugated

anti-CD274 (PD-L1) (C-Term) antibody
KO Validated PD-L1 Reactivity: Human WB, FACS, ICC, IF, IHC (p), IHC (fro) Host: Rabbit Polyclonal unconjugated

anti-CD274 (PD-L1) (AA 19-238) antibody
PD-L1 Reactivity: Human WB, IHC, IF Host: Rabbit Polyclonal unconjugated

Application Notes

IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions

For Research Use only
Format

Liquid

Concentration

1 μg/μL

Buffer

Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative

ProClin

Precaution of Use

This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage

-20 °C

Storage Comment

Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date

12 months
Target

PD-L1 (CD274 (PD-L1))

Alternative Name

PD-L1 (PD-L1 Products)

Synonyms

B7-H antibody, B7H1 antibody, PD-L1 antibody, PDCD1L1 antibody, PDCD1LG1 antibody, PDL1 antibody, A530045L16Rik antibody, B7h1 antibody, Pdcd1l1 antibody, Pdcd1lg1 antibody, Pdl1 antibody, RGD1566211 antibody, CD274 molecule antibody, CD274 antigen antibody, programmed cell death 1 ligand 2 antibody, CD274 antibody, Cd274 antibody, PDCD1LG2 antibody

Background

Synonyms: CD274, B7 H, B7 H1, B7 homolog 1, B7-H1, B7H, B7H1, CD 274, CD274 antigen, CD274 Molecule, MGC142294, MGC142296, OTTHUMP00000021029, PD L1, PD1L1_HUMAN, PD1L1_Mouse, PDCD1 ligand 1, PDCD1L1, PDCD1LG1, PDL 1, PDL1, Programmed cell death 1 ligand 1, Programmed death ligand 1, RGD1566211.
Background: Involved in the costimulatory signal, essential for T-cell proliferation and production of IL10 and IFNG, in an IL2-dependent and a PDCD1-independent manner. Interaction with PDCD1 inhibits T-cell proliferation and cytokine production.

Gene ID

29126

UniProt

Q9EP73

Pathways

Cancer Immune Checkpoints