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IMPACT antibody (AA 21-120) (AbBy Fluor® 488)

IMPACT Reactivity: Mouse, Rat WB, IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN6977475
  • Target See all IMPACT Antibodies
    IMPACT (Impact Homolog (IMPACT))
    Binding Specificity
    • 14
    • 14
    • 7
    • 6
    • 2
    • 1
    AA 21-120
    Reactivity
    • 23
    • 15
    • 15
    Mouse, Rat
    Host
    • 35
    • 2
    Rabbit
    Clonality
    • 37
    Polyclonal
    Conjugate
    • 10
    • 5
    • 4
    • 4
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This IMPACT antibody is conjugated to AbBy Fluor® 488
    Application
    • 33
    • 20
    • 12
    • 12
    • 3
    • 3
    • 2
    • 1
    • 1
    Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Mouse, Rat
    Predicted Reactivity
    Human,Dog,Cow,Sheep,Rabbit
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human IMPACT
    Isotype
    IgG
    Top Product
    Discover our top product IMPACT Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    IMPACT (Impact Homolog (IMPACT))
    Alternative Name
    IMPACT (IMPACT Products)
    Synonyms
    zgc:103672 antibody, Ximpact antibody, impact-A antibody, RWDD5 antibody, impact-a antibody, E430016J11Rik antibody, impact RWD domain protein antibody, impact antibody, impact RWD domain protein L homeolog antibody, impact, RWD domain protein antibody, IMPACT antibody, impact antibody, EDI_298310 antibody, impact.L antibody, Impact antibody
    Background

    Synonyms: Protein IMPACT, IMPACT, Imprinted and ancient gene protein homolog

    Background: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis (By similarity). May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis (By similarity). Through its action on GCN2, may also facilitate neuritogenesis (By similarity).

    Gene ID
    55364
    UniProt
    Q9P2X3
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