IMPACT antibody (AA 21-120) (AbBy Fluor® 488)
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- Target See all IMPACT Antibodies
- IMPACT (Impact Homolog (IMPACT))
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Binding Specificity
- AA 21-120
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Reactivity
- Mouse, Rat
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This IMPACT antibody is conjugated to AbBy Fluor® 488
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Application
- Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
- Cross-Reactivity
- Mouse, Rat
- Predicted Reactivity
- Human,Dog,Cow,Sheep,Rabbit
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human IMPACT
- Isotype
- IgG
- Top Product
- Discover our top product IMPACT Primary Antibody
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- Application Notes
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IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200 - Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- IMPACT (Impact Homolog (IMPACT))
- Alternative Name
- IMPACT (IMPACT Products)
- Synonyms
- zgc:103672 antibody, Ximpact antibody, impact-A antibody, RWDD5 antibody, impact-a antibody, E430016J11Rik antibody, impact RWD domain protein antibody, impact antibody, impact RWD domain protein L homeolog antibody, impact, RWD domain protein antibody, IMPACT antibody, impact antibody, EDI_298310 antibody, impact.L antibody, Impact antibody
- Background
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Synonyms: Protein IMPACT, IMPACT, Imprinted and ancient gene protein homolog
Background: Translational regulator that ensures constant high levels of translation under amino acid starvation. Acts by interacting with GCN1/GCN1L1, thereby preventing activation of GCN2 protein kinases (EIF2AK1 to 4) and subsequent down-regulation of protein synthesis (By similarity). May be required to regulate translation in specific neuronal cells under amino acid starvation conditions by preventing GCN2 activation and therefore ATF4 synthesis (By similarity). Through its action on GCN2, may also facilitate neuritogenesis (By similarity).
- Gene ID
- 55364
- UniProt
- Q9P2X3
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