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Importin 8 antibody (AA 1-100) (AbBy Fluor® 488)

IPO8 Reactivity: Rat IF (cc), IF (p) Host: Rabbit Polyclonal AbBy Fluor® 488
Catalog No. ABIN6977751
  • Target See all Importin 8 (IPO8) Antibodies
    Importin 8 (IPO8)
    Binding Specificity
    • 14
    • 2
    • 2
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    AA 1-100
    Reactivity
    • 18
    • 16
    • 4
    • 2
    • 2
    • 2
    • 1
    Rat
    Host
    • 32
    • 1
    • 1
    Rabbit
    Clonality
    • 33
    • 1
    Polyclonal
    Conjugate
    • 14
    • 2
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    • 1
    This Importin 8 antibody is conjugated to AbBy Fluor® 488
    Application
    • 12
    • 12
    • 9
    • 7
    • 4
    • 3
    • 3
    • 3
    • 3
    • 1
    • 1
    Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))
    Cross-Reactivity
    Rat
    Predicted Reactivity
    Human,Mouse,Cow,Sheep,Pig
    Purification
    Purified by Protein A.
    Immunogen
    KLH conjugated synthetic peptide derived from human Importin 8
    Isotype
    IgG
    Top Product
    Discover our top product IPO8 Primary Antibody
  • Application Notes
    IF(IHC-P) 1:50-200
    IF(IHC-F) 1:50-200
    IF(ICC) 1:50-200
    Restrictions
    For Research Use only
  • Format
    Liquid
    Concentration
    1 μg/μL
    Buffer
    Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
    Preservative
    ProClin
    Precaution of Use
    This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
    Storage
    -20 °C
    Storage Comment
    Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
    Expiry Date
    12 months
  • Target
    Importin 8 (IPO8)
    Alternative Name
    Importin 8 (IPO8 Products)
    Synonyms
    IPO8 antibody, si:ch211-116i17.1 antibody, RANBP8 antibody, 6230418K12Rik antibody, Abcc10 antibody, C130009K11Rik antibody, MRP7 antibody, OM-1 antibody, Om1 antibody, Ranbp8 antibody, importin 8 antibody, IPO8 antibody, ipo8 antibody, Ipo8 antibody
    Background

    Synonyms: FLJ26580, Imp 8, Imp8, Importin-8, Importin8, IPO 8, IPO8, IPO8_HUMAN, Ran binding protein 8, RAN BP8, Ran-binding protein 8, RANBP 8, RANBP8.

    Background: Seems to function in nuclear protein import, either by acting as autonomous nuclear transport receptor or as an adapter-like protein in association with the importin-beta subunit KPNB1. Acting autonomously, is thought to serve itself as receptor for nuclear localization signals (NLS) and to promote translocation of import substrates through the nuclear pore complex (NPC) by an energy requiring, Ran-dependent mechanism. At the nucleoplasmic side of the NPC, Ran binds to importin, the importin/substrate complex dissociates and importin is re-exported from the nucleus to the cytoplasm where GTP hydrolysis releases Ran. The directionality of nuclear import is thought to be conferred by an asymmetric distribution of the GTP- and GDP-bound forms of Ran between the cytoplasm and nucleus. In vitro mediates the nuclear import of SRP19.

    Gene ID
    10526
    UniProt
    O15397
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