SPATA5L1 antibody (AA 221-320) (Alexa Fluor 555)

Catalog No. ABIN6978418

Product Details anti-SPATA5L1 Antibody (Alexa Fluor 555)

Target: SPATA5L1 (Spermatogenesis Associated 5-Like 1 (SPATA5L1))

Binding Specificity: AA 221-320

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SPATA5L1 antibody is conjugated to Alexa Fluor 555

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat,Dog,Rabbit

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SPATA5L1

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SPATA5L1

Target: SPATA5L1 (Spermatogenesis Associated 5-Like 1 (SPATA5L1))

Alternative Name: SPATA5L1 (SPATA5L1 Products)

Synonyms: spermatogenesis associated 5 like 1 antibody, SPATA5L1 antibody

Background:

Synonyms: FLJ12286, MGC5347, SPA5L_HUMAN, SPATA5L1, Spermatogenesis-associated protein 5-like protein 1.

Background: SPATA5L1 is a 753 amino acid protein belonging to the AAA ATPase family and AFG2 subfamily. Single nucleotide polymorphisms (SNPs) present in SPATA5L1 at the glycine amidinotransferase (GATM)-SPATA5L1 locus have been found to correlate with glomerular filtration rate (GFR), having significant implications for kidney disease research. SPATA5L1 localizes to cytoplasm and exists as three alternatively spliced isoforms. The gene encoding SPATA5L1 maps to human chromosome 15q21.1. Encoding more than 700 genes, chromosome 15 is made up of approximately 106 million base pairs and comprises about 3 % of the human genome. Tay-Sachs disease is a lethal disorder associated with mutations of the HEXA gene, which is encoded by chromosome 15. Marfan syndrome is associated with chromosome 15 through the FBN1 gene.

Gene ID: 79029

UniProt: Q9BVQ7