Csfv Envelope Glycoprotein E2 antibody (Alexa Fluor 594)

Catalog No. ABIN6979410

Product Details

Target: Csfv Envelope Glycoprotein E2

Reactivity: Classical Swine Fever Virus (CSFV)

Host: Goat

Clonality: Polyclonal

Conjugate: Alexa Fluor 594

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Cross-Reactivity: Virus

Purification: Purified by Protein A.

Immunogen: Recombinded CSFV E2 protein, classical swine fever virus (strain Alfort) (CSFV) (Hog cholera virus)

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: Csfv Envelope Glycoprotein E2

Alternative Name: CSFV E2 Protein

Target Type: Viral Protein

Background:

Synonyms: CSFV Polyprotein, CSFV E2 protein, CSFV E2, polyprotein [Classical swine fever virus], polyprotein, CSFV polyprotein, E2, Envelope glycoprotein E2, CSFV Envelope glycoprotein E2, Classical swine fever virus E2, Classical swine fever virus Envelope glycoprotein E2, structural protein E2 [Classical swine fever virus].

Background: E(rns), E1 and E2 are responsible of cell attachment and subsequent fusion of viral and cellular membrane. P7 forms a leader sequence to properly orient NS2 in the membrane. Uncleaved NS2-3 is required for production of infectious virus. NS2 protease seems to play a vital role in viral RNA replication control and in the pathogenicity of the virus. NS3 displays three enzymatic activities: serine protease, NTPase and RNA helicase. NS4A is a cofactor for the NS3 protease activity. RNA-directed RNA polymerase NS5 replicates the viral (+) and (-) genome.

UniProt: P19712