SNAIL antibody (AA 1-100) (Alexa Fluor 647)

Catalog No. ABIN6980315

Product Details anti-SNAIL Antibody (Alexa Fluor 647)

Target: SNAIL (SNAI1)

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: This SNAIL antibody is conjugated to Alexa Fluor 647

Application: Flow Cytometry (FACS)

Cross-Reactivity: Human

Predicted Reactivity: Mouse,Rat

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human SNAIL

Isotype: IgG

Application Details

Application Notes: FCM 1:20-100

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details for SNAIL

Target: SNAIL (SNAI1)

Alternative Name: SNAIL (SNAI1 Products)

Synonyms: SLUGH2 antibody, SNA antibody, SNAH antibody, SNAIL antibody, SNAIL1 antibody, dJ710H13.1 antibody, AI194338 antibody, Sna antibody, Sna1 antibody, Snail antibody, Snail1 antibody, SNAI1 antibody, BG:DS01845.1 antibody, CG3956 antibody, Dmel\\CG3956 antibody, Sco antibody, br28 antibody, br29 antibody, l(2)35Db antibody, l(2)br28 antibody, l(2)br29 antibody, l(3)br28 antibody, l35Db antibody, sn antibody, Xsnail antibody, sna antibody, snail1 antibody, xSna antibody, Snai antibody, sna2 antibody, snail2 antibody, cb643 antibody, sna-1 antibody, sna1 antibody, snai1 antibody, snail1a antibody, zgc:109820 antibody, snail family transcriptional repressor 1 antibody, snail family zinc finger 1 antibody, snail homolog 1 (Drosophila) antibody, snail antibody, zinc-finger transcription factor Snail antibody, snail family zinc finger 1 S homeolog antibody, protein escargot antibody, transcription factor protein antibody, snail zinc finger protein antibody, snail family zinc finger 1b antibody, snail family zinc finger 1a antibody, SNAI1 antibody, Snai1 antibody, sna antibody, snail antibody, snai1.S antibody, LOC410464 antibody, snai1b antibody, snai1a antibody

Background:

Synonyms: dJ710H13.1, Protein sna, Protein snail homolog, SLUGH2, SNA, Sna protein, SNAH, SNAI1, SNAI 1, Snail homolog 1 (Drosophila), Zinc finger protein SNAI1, SNAI1_HUMAN, Protein snail homolog 1, dJ710H13.1, SNAIL, SNAIL1, Protein sna.

Background: The zinc finger transcription factor 'SNAIL' was first identified in Drosophila and, along with 'twist', a basic helix-loop-helix transcription factor, is indispensable for mesoderm formation. SNAIL is a repressor of mouse E-cadherin transcription, with expression of SNAIL inversely correlated with expression of E-cadherin. Abnormal expression of SNAIL could underlie the tumorigenic conversion of epithelia associated with loss of E-cadherin expression through screening mouse and human cell lines and by in situ hybridization of primary human tumors undergoing malignant progression.

Gene ID: 6615

UniProt: O95863

Pathways: Negative Regulation of intrinsic apoptotic Signaling