GIPC1 antibody (AA 171-270) (Biotin)

Catalog No. ABIN6982872

Product Details anti-GIPC1 Antibody (Biotin)

Target: GIPC1 (GIPC PDZ Domain Containing Family, Member 1 (GIPC1))

Binding Specificity: AA 171-270

Reactivity: Mouse, Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This GIPC1 antibody is conjugated to Biotin

Application: Western Blotting (WB)

Cross-Reactivity: Mouse, Rat

Predicted Reactivity: Human,Cow,Sheep

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human GIPC1?

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GIPC1

Target: GIPC1 (GIPC PDZ Domain Containing Family, Member 1 (GIPC1))

Alternative Name: GIPC1 (GIPC1 Products)

Synonyms: C19orf3 antibody, GIPC antibody, GLUT1CBP antibody, Hs.6454 antibody, IIP-1 antibody, NIP antibody, RGS19IP1 antibody, SEMCAP antibody, SYNECTIIN antibody, SYNECTIN antibody, TIP-2 antibody, XGIPC antibody, kermit antibody, rgs19ip1 antibody, gipc3 antibody, iip-1 antibody, Kermit antibody, semcap antibody, glut1cbp antibody, synectiin antibody, GIPC1 antibody, Glut1CIP antibody, Rgs19ip1 antibody, Semcap1 antibody, TaxIP2 antibody, Gipc antibody, Rgs19 antibody, GIPC PDZ domain containing family member 1 antibody, GIPC PDZ domain containing family member 1 L homeolog antibody, GIPC PDZ domain containing family, member 1 antibody, RGS-GAIP interacting protein GIPC antibody, PDZ domain-containing protein GIPC3 antibody, putative rgs-gaip interacting protein gipc antibody, GIPC1 antibody, gipc1.L antibody, gipc1 antibody, Gipc1 antibody, LOC692815 antibody, LOC5576629 antibody, Smp_170870 antibody

Background:

Synonyms: C19ORF3, Chromosome 19 open reading frame 3, GIPC, GLUT1 C terminal binding protein, GLUT1CBP, IGF 1 receptor interacting protein 1, IIP 1, IIP1, NIP, PDZ domain-containing protein GIPC1, Regulator of G protein signalling 19 interacting protein 1, RGS19 interacting protein 1, RGS19IP1, SEMCAP, SYNECTIIN, Tax interaction protein 2, TIP 2, GIPC1_HUMAN.

Background: GIPC, for GAIP interacting protein at the C terminus (also designated SEMCAP-1 or synectin), is a PDZ domain containing protein that interacts with RGS-GAIP, a GTPase-activating protein (GAP) for G(a i) subunits. GIPC was also identified as TIP-2, a protein that interacts with the viral oncoprotein TAX, which transactivates viral and cellular promoters through interactions with various transcription factors. PDZ domain-containing proteins are primarily localized to cell-cell junctions in epithelial cells and neurons where they coordinate the assembly of multiprotein complexes. GIPC specifically localizes to clusters of vesicles near the plasma membrane and participates in G protein-coupled signaling pathway involved in regulating clathrin-coated vesicular trafficking. GIPC also associates with membrane bound semaphorin F (M-SemF), which is involved in neuronal axon growth, and it appears to regulate the subcellular distribution of M-SemF in the brain.

Gene ID: 10755

UniProt: O14908

Pathways: Dicarboxylic Acid Transport