COPG1, COPG2 (AA 1-100) antibody (Cy3)

Catalog No. ABIN6983310

Product Details

Target: COPG1, COPG2

Binding Specificity: AA 1-100

Reactivity: Human

Host: Rabbit

Clonality: Polyclonal

Conjugate: Cy3

Application: Western Blotting (WB), Immunofluorescence (Cultured Cells) (IF (cc)), Immunofluorescence (Paraffin-embedded Sections) (IF (p))

Predicted Reactivity: Human,Mouse,Rat,Cow

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human COPG2

Isotype: IgG

Application Details

Application Notes: IF(IHC-P) 1:50-200
IF(IHC-F) 1:50-200
IF(ICC) 1:50-200

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.

Expiry Date: 12 months

Target Details

Target: COPG1, COPG2

Alternative Name: COPG1 + COPG2

Background:

Synonyms: 2 COP, Coat protein nonclathrin gamma 2 cop, Coatomer protein complex subunit gamma 2, Coatomer subunit gamma 2, Coatomer subunit gamma-2, COPG 2, Copg2, COPG2_HUMAN, DKFZp761N09121, FLJ11781, Gamma 2 coat protein, Gamma 2 COP, Gamma-2-coat protein, Gamma-2-COP, Coatomer subunit gamma-1, COPG1, Gamma-1-coat protein, Gamma-1-COP, COPG

Background: The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin-coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. In mammals, the coatomer can only be recruited by membranes associated to ADP-ribosylation factors (ARFs), which are small GTP-binding proteins, the complex also influences the Golgi structural integrity, as well as the processing, activity, and endocytic recycling of LDL receptors.

Gene ID: 22820, 26958

UniProt: Q9Y678, Q9UBF2