ADH5 antibody (AA 301-374) (PE)
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- Target See all ADH5 Antibodies
- ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))
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Binding Specificity
- AA 301-374
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Reactivity
- Mouse
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Host
- Rabbit
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Clonality
- Polyclonal
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Conjugate
- This ADH5 antibody is conjugated to PE
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Application
- Flow Cytometry (FACS)
- Cross-Reactivity
- Mouse
- Predicted Reactivity
- Human,Rat
- Purification
- Purified by Protein A.
- Immunogen
- KLH conjugated synthetic peptide derived from human ADH5
- Isotype
- IgG
- Top Product
- Discover our top product ADH5 Primary Antibody
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- Application Notes
- FCM 1:20-100
- Restrictions
- For Research Use only
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- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C. Aliquot into multiple vials to avoid repeated freeze-thaw cycles.
- Expiry Date
- 12 months
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- Target
- ADH5 (Alcohol Dehydrogenase 5 (Class III), chi Polypeptide (ADH5))
- Alternative Name
- ADH5 (ADH5 Products)
- Synonyms
- ADH2 antibody, ADH-3 antibody, ADHX antibody, FALDH antibody, FDH antibody, GSH-FDH antibody, GSNOR antibody, ADH1C antibody, ADH3 antibody, wu:fb60b11 antibody, Adh-5 antibody, Adh3 antibody, adh-3 antibody, adh3 antibody, adh5 antibody, adhx antibody, fdh antibody, gsnor antibody, ADH4 antibody, ADH5 antibody, alcohol dehydrogenase 1B (class I), beta polypeptide antibody, alcohol dehydrogenase 5 (class III), chi polypeptide antibody, alcohol dehydrogenase 5 antibody, alcohol dehydrogenase 5 (class III), chi polypeptide L homeolog antibody, alcohol dehydrogenase class-3 antibody, ADH1B antibody, ADH5 antibody, adh5 antibody, Adh5 antibody, adh5.L antibody, LOC101112223 antibody
- Background
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Synonyms: ADH 3, ADH5, ADHX, ADHX_HUMAN, Alcohol dehydrogenase class III chi polypeptide, alcohol dehydrogenase 5 class III chi polypeptide, Alcohol dehydrogenase 5, Alcohol dehydrogenase class 3, Alcohol dehydrogenase class chi chain, Alcohol dehydrogenase class III, Alcohol dehydrogenase class-3, Alcohol dehydrogenase class-III, class III alcohol dehydrogenase 5 chi subunit, FALDH, FDH, formaldehyde dehydrogenase, Glutathione dependent formaldehyde dehydrogenase, Glutathione-dependent formaldehyde dehydrogenase, GSH-FDH, hydroxymethyllutathione dehydrogenase, S-hydroxymethylglutathione dehydrogenase.
Background: The alcohol dehydrogenase family of proteins metabolize a wide variety of substrates, including retinol, hydroxysteroids, ethanol, aliphatic alcohols and lipid peroxidation products. ADH5 (alcohol dehydrogenase 5 (class III)), also known as FDH (formaldehyde dehydrogenase), ADHX, ADH-3 or GSNOR, is a 374 amino acid cytoplasmic protein that belongs to the class III subfamily of alcohol dehydrogenases. Expressed ubiquitously, ADH5 uses iron as a cofactor to catalytically oxidize both long-chain primary alcohols and S-hydroxymethyl-glutathione, a product formed spontaneously between formaldehyde and glutathione. ADH5 exists as a homodimer and, via its ability to oxidize S-hydroxymethyl-glutathione and, thus, eliminate formaldehyde, functions as an important component of cellular metabolism. Genetic variations in the gene encoding ADH5 may affect drug and alcohol dependence in humans.
- Gene ID
- 128
- UniProt
- P11766
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