GOT2 antibody

Catalog No. ABIN6989684

Product Details anti-GOT2 Antibody

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Reactivity: Human, Mouse, Rat

Host: Rabbit

Clonality: Monoclonal

Conjugate: This GOT2 antibody is un-conjugated

Application: Western Blotting (WB), Flow Cytometry (FACS), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Cross-Reactivity: Human, Mouse, Rat

Purification: Purified by Protein A.

Immunogen: Synthetic Peptide within Human GOT2.

Clone: 4H6

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
FCM 1:20-100
IHC-P 1:200-400

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for GOT2

Target: GOT2 (Glutamic-Oxaloacetic Transaminase 2, Mitochondrial (Aspartate Aminotransferase 2) (GOT2))

Alternative Name: GOT2 (GOT2 Products)

Synonyms: KAT4 antibody, KATIV antibody, mitAAT antibody, AI789014 antibody, Got-1 antibody, cAspAT antibody, cCAT antibody, AL022787 antibody, FABP-pm antibody, Got-2 antibody, mAspAT antibody, ASPATA antibody, got2 antibody, zgc:66329 antibody, fj40h07 antibody, wu:fj40h07 antibody, zgc:56425 antibody, glutamic-oxaloacetic transaminase 2 antibody, glutamic-oxaloacetic transaminase 1, soluble antibody, glutamatic-oxaloacetic transaminase 2, mitochondrial antibody, glutamic-oxaloacetic transaminase 2a, mitochondrial antibody, glutamic-oxaloacetic transaminase 2 L homeolog antibody, Aspartate amino transferase activity antibody, glutamic-oxaloacetic transaminase 2b, mitochondrial antibody, GOT2 antibody, got2 antibody, Got1 antibody, Got2 antibody, got2a antibody, got2.L antibody, AST antibody, got2b antibody

Background:

Synonyms: AATM_HUMAN antibody, AL022787 antibody, Aspartate aminotransferase 2 antibody, Aspartate aminotransferase antibody, Aspartate aminotransferase, mitochondrial antibody, Aspartate transaminase 2 antibody, ASPATA antibody, EC 2.6.1.1 antibody, FABP 1 antibody,

Background: GOT2 [Glutamate oxaloacetate transaminase] is a ubiquitous pyridoxal phosphate dependent enzyme which exists in both mitochondrial and cytosolic forms. The enzyme plays an important role in amino acid metabolism and in the urea and tricarboxylic acid cycles. The 2 isoenzymes are homodimeric. In liver about 80 % of the enzyme activity is mitochondrial in origin, whereas in serum the enzyme activity is largely cytosolic. Although the mitochondrial and soluble forms of GOT are coded by different chromosomes, the 2 show close homology in amino acid sequence and were presumably derived from a common ancestral gene. Serum GOT [with SGPT] levels are usually elevated in states of hepatocellular injury (injury to the liver cells), the highest levels are associated with hepatitis of a viral origin. High levels are also found after myocardial infarction, when SGPT levels are lower.

Gene ID: 2806

UniProt: P00505

Pathways: Monocarboxylic Acid Catabolic Process