Histone H1.3+Histone H1.4 (pThr17) antibody
-
- Target
- Histone H1.3+Histone H1.4
- Binding Specificity
- pThr17
- Reactivity
- Human, Mouse, Rat
- Host
- Rabbit
- Clonality
- Monoclonal
- Application
- Immunofluorescence (Cultured Cells) (IF (cc)), Immunohistochemistry (IHC), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p)), Western Blotting (WB)
- Cross-Reactivity
- Human, Mouse, Rat
- Purification
- Purified by Protein A.
- Immunogen
- Synthetic phospho-Peptide corresponding to residues surrounding Thr17 of human H1.4.
- Clone
- 5H3
- Isotype
- IgG
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- Application Notes
-
WB 1:300-5000
IHC-P 1:200-400
IF(ICC) 1:50-200
IHC() - Restrictions
- For Research Use only
-
- Format
- Liquid
- Concentration
- 1 μg/μL
- Buffer
- Aqueous buffered solution containing 1xTBS ( pH 7.4), 1 % BSA, 40 %Glycerol and 0.05 % Sodium Azide.
- Preservative
- ProClin
- Precaution of Use
- This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.
- Storage
- -20 °C
- Storage Comment
- Store at -20°C for 12 months.
- Expiry Date
- 12 months
-
- Target
- Histone H1.3+Histone H1.4
- Background
-
Synonyms: Histone H1.3, Histone H1c, Histone H1s-2, HIST1H1DH1F3, Histone H1.4, Histone H1b, Histone H1s-4, HIST1H1EH1F4
Background: Histone H1b are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction of a linker histone, H1, with the DNA between the nucleosomes to form higher order chromatin structures. This gene is intronless and encodes a member of the histone H1 family. Transcripts from this gene lack polyA tails but instead contain a palindromic termination element. This gene is found in the large histone gene cluster on chromosome 6.
- Gene ID
- 3008
- UniProt
- P10412
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